Clinical Considerations on Anticoagulation Management in Cardiovascular Diseases During Pregnancy

被引：1

作者：

Goland, Sorel ^{[1
]}

Zilberman, Liaz ^{[1
]}

Elkayam, Uri ^{[2
]}

机构：

[1] Kaplan Med Ctr, Dept Cardiol, IL-76100 Rehovot, Israel

[2] Univ So Calif, Dept Med, Div Cardiovasc Dis, Los Angeles, CA USA

来源：

DRUG DEVELOPMENT RESEARCH | 2013年 / 74卷 / 08期

关键词：

anticoagulation; pregnancy; cardiovascular diseases; MOLECULAR-WEIGHT HEPARIN; MECHANICAL HEART-VALVES; MASSIVE PULMONARY-EMBOLISM; TISSUE-PLASMINOGEN ACTIVATOR; VENOUS THROMBOEMBOLISM; PERIPARTUM CARDIOMYOPATHY; HEMOSTATIC CHANGES; RISK-FACTORS; WOMEN; WARFARIN;

D O I：

10.1002/ddr.21113

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Pregnancy-associated thrombosis is an important cause of morbidity and mortality during pregnancy. All anticoagulation options are associated with risks and benefits. Thus, although anticoagulation therapy is an important component of the management of thrombotic complications in pregnancy, it is associated with fetal and maternal complications. Therefore, pregnancy poses a serious therapeutic dilemma for both physicians and their patients. This review summarizes the available data on anticoagulation therapy for thromboembolic prophylaxis in pregnant women focusing on cardiovascular disorders, especially on treatment strategy in pregnant women with mechanical heart valves. (C) 2013 Wiley Periodicals, Inc.

引用

页码：541 / 552

页数：12

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