Analysis of combinatorial libraries using electrospray Fourier transform ion cyclotron resonance mass spectrometry

被引：0
作者：
Nawrocki, JP
Wigger, M
Watson, CH
Hayes, TW
Senko, MW
Benner, SA
Eyler, JR
机构：
[1] UNIV FLORIDA, DEPT CHEM, GAINESVILLE, FL 32611 USA
[2] SWISS FED INST TECHNOL, DEPT CHEM, CH-8092 ZURICH, SWITZERLAND
[3] NATL HLTH MAGNET FIELD LAB, TALLAHASSEE, FL 32306 USA
来源：
RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1996年 / 10卷 / 14期
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D O I：
暂无
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Electrospray ionization coupled with Fourier transform ion cyclotron resonance (FTICR) mass spectrometry has been used to provide information about complete combinatorial libraries of small peptides containing 10(3)-10(4) components, The fidelity of attempted synthesis steps can be ascertained rapidly, and, when the extremely high resolution FTICR mass spectra are combined with appropriate computer simulation, both diversity and degeneracy of the libraries as synthesized can be assessed.
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页码：1860 / 1864
页数：5
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