The Expanding and Unexpected Functions of Mitochondria Contact Sites

被引:88
作者
Lackner, Laura L. [1 ]
机构
[1] Northwestern Univ, Dept Mol Biosci, Evanston, IL 60208 USA
基金
美国国家卫生研究院;
关键词
ENDOPLASMIC-RETICULUM; ER-MITOCHONDRIA; PLASMA-MEMBRANE; SMP DOMAINS; MITOFUSIN; PROTEIN; ORGANELLE; NUM1; INHERITANCE; VACUOLE;
D O I
10.1016/j.tcb.2019.02.009
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Mitochondria make functionally relevant contacts with most, if not all, other organelles in the cell. These contacts impact on mitochondrial behavior and function as well as on a wide variety of cellular functions. Many recent advances have been made in the rapidly growing field of mitochondria contact site biology, and these advances have expanded the known functions of mitochondria contact sites in exciting and unexpected ways.
引用
收藏
页码:580 / 590
页数:11
相关论文
共 93 条
[41]   Homology of SMP domains to the TULIP superfamily of lipid-binding proteins provides a structural basis for lipid exchange between ER and mitochondria [J].
Kopec, Klaus O. ;
Alva, Vikram ;
Lupas, Andrei N. .
BIOINFORMATICS, 2010, 26 (16) :1927-1931
[42]   An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen [J].
Kornmann, Benoit ;
Currie, Erin ;
Collins, Sean R. ;
Schuldiner, Maya ;
Nunnari, Jodi ;
Weissman, Jonathan S. ;
Walter, Peter .
SCIENCE, 2009, 325 (5939) :477-481
[43]   An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2 [J].
Korobova, Farida ;
Ramabhadran, Vinay ;
Higgs, Henry N. .
SCIENCE, 2013, 339 (6118) :464-467
[44]   A conserved mechanism for mitochondria-dependent dynein anchoring [J].
Kraft, Lauren M. ;
Lackner, Laura L. .
MOLECULAR BIOLOGY OF THE CELL, 2019, 30 (05) :691-702
[45]   Mitochondria-driven assembly of a cortical anchor for mitochondria and dynein [J].
Kraft, Lauren M. ;
Lackner, Laura L. .
JOURNAL OF CELL BIOLOGY, 2017, 216 (10) :3061-3071
[46]   VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites [J].
Kumar, Nikit ;
Leonzino, Marianna ;
Hancock-Cerutti, William ;
Horenkamp, Florian A. ;
Li, Peiqi ;
Lees, Joshua A. ;
Wheeler, Heather ;
Reinisch, Karin M. ;
De Camilli, Pietro .
JOURNAL OF CELL BIOLOGY, 2018, 217 (10) :3625-3639
[47]   Determinants and Functions of Mitochondrial Behavior [J].
Labbe, Katherine ;
Murley, Andrew ;
Nunnari, Jodi .
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30, 2014, 30 :357-391
[48]   Shaping the dynamic mitochondrial network [J].
Lackner, Laura L. .
BMC BIOLOGY, 2014, 12
[49]   Endoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondria [J].
Lackner, Laura L. ;
Ping, Holly ;
Graef, Martin ;
Murley, Andrew ;
Nunnari, Jodi .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (06) :E458-E467
[50]   A Conserved Endoplasmic Reticulum Membrane Protein Complex (EMC) Facilitates Phospholipid Transfer from the ER to Mitochondria [J].
Lahiri, Sujoy ;
Chao, Jesse T. ;
Tavassoli, Shabnam ;
Wong, Andrew K. O. ;
Choudhary, Vineet ;
Young, Barry P. ;
Loewen, Christopher J. R. ;
Prinz, William A. .
PLOS BIOLOGY, 2014, 12 (10)