Serology-Basec Diagnostics for the Control of Bovine Neosoorosis

被引:40
作者
Guido, Stefano [1 ,2 ]
Katzer, Frank [1 ]
Nanjiani, Ian [3 ]
Milne, Elspeth [2 ]
Innes, Elisabeth A. [1 ]
机构
[1] Moredun Res Inst, Pentlands Sci Pk, Penicuik EH26 0PZ, Midlothian, Scotland
[2] Univ Edinburgh, Royal Dick Sch Vet Studies, Roslin EH25 9RG, Midlothian, Scotland
[3] Dawes Farm, Westpoint Vet Grp, Bognor Rd, Warnham RH12 3SH, W Sussex, England
关键词
NEOSPORA-CANINUM INFECTION; LINKED-IMMUNOSORBENT-ASSAY; DAIRY-CATTLE; TRANSPLACENTAL INFECTION; VERTICAL TRANSMISSION; AGGLUTINATION-TEST; IN-VITRO; TACHYZOITE ANTIGENS; RECOMBINANT NCSAG1; TOXOPLASMA-GONDII;
D O I
10.1016/j.pt.2015.11.014
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The protozoan Neospora caninum is a primary infectious cause of abortion in cattle that causes significant economic losses worldwide. Because effective vaccines and licensed pharmacological treatments are currently unavailable, control measures rely on biosecurity and management practice. Serological diagnosis plays a crucial role in the identification of infected animals and several tests have been developed. However, owing to the particular dynamics of the host -parasite interaction and to the characteristics of the currently used diagnostic tools, a proportion of infected cattle may not be reliably identified, and can potentially undermine efforts towards the control of bovine neosporosis. Current diagnostic methods for N, caninum infection in cattle and the advances necessary to support effective control strategies are discussed.
引用
收藏
页码:131 / 143
页数:13
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