Modeling Spatial Spread of Infectious Diseases with a Fixed Latent Period in a Spatially Continuous Domain

被引:80
作者
Li, Jing [1 ,2 ]
Zou, Xingfu [1 ]
机构
[1] Univ Western Ontario, Dept Appl Math, London, ON N6A 5B7, Canada
[2] Univ Ottawa, Dept Math & Stat, Ottawa, ON K1N 6N5, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
Latent period; Diffusion; Traveling waves; Wave speed; Spread speed; Non-local infection; TRAVELING-WAVE SOLUTIONS; TUBERCULOSIS MYCOBACTERIUM-BOVIS; LOTKA-VOLTERRA EQUATIONS; EPIDEMIC MODEL; PATCHY ENVIRONMENT; MELES-MELES; TRANSMISSION; CONNECTION; DISPERSAL; EXISTENCE;
D O I
10.1007/s11538-009-9457-z
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In this paper, with the assumptions that an infectious disease in a population has a fixed latent period and the latent individuals of the population may diffuse, we formulate an SIR model with a simple demographic structure for the population living in a spatially continuous environment. The model is given by a system of reaction-diffusion equations with a discrete delay accounting for the latency and a spatially non-local term caused by the mobility of the individuals during the latent period. We address the existence, uniqueness, and positivity of solution to the initial-value problem for this type of system. Moreover, we investigate the traveling wave fronts of the system and obtain a critical value c* which is a lower bound for the wave speed of the traveling wave fronts. Although we can not prove that this value is exactly the minimal wave speed, numeric simulations seem to suggest that it is. Furthermore, the simulations on the PDE model also suggest that the spread speed of the disease indeed coincides with c*. We also discuss how the model parameters affect c*.
引用
收藏
页码:2048 / 2079
页数:32
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