Acute coronary syndrome and diabetic keto acidosis: the chicken or the egg?

被引：17

作者：

Kaefer, Keitiane ^{[1
]}

Botta, Ilaria ^{[2
]}

Mugisha, Aude ^{[1
]}

Berdaoui, Brahim ^{[2
]}

De Bels, David ^{[1
]}

Attou, Rachid ^{[1
]}

Honore, Patrick M. ^{[1
]}

Redant, Sebastien ^{[1
]}

机构：

[1] Univ Libre Bruxelles, Brugmann Univ Hosp, Dept Intens Care, Brussels, Belgium

[2] Univ Libre Bruxelles, Brugmann Univ Hosp, Dept Cardiol, Brussels, Belgium

来源：

ANNALS OF TRANSLATIONAL MEDICINE | 2019年 / 7卷 / 16期

关键词：

Acute coronary syndrome (ACS); acute metabolic acidosis; diabetic keto acidosis; HYPERGLYCEMIC CRISES; ADULT PATIENTS; TROPONIN; KETOACIDOSIS;

D O I：

10.21037/atm.2019.07.38

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We sought to describe two cases of diabetic ketoacidosis (DKA) with elevated troponin. The association of DKA with myocardial infarction (MI) is very frequent. We therefore decide to look deeply in the potential mechanisms behind this strong relationship. We did review the potential role of severe acidosis, intracellular calcium, the counter-regulatory hormones and the potential of the free fatty acid release. Those two conditions can trigger each other and it is often difficult to know which condition appear first. Ultimately, it stands to reason that the message for the clinician should be that a troponin elevation in a DKA patient should always be considered as a coronary abnormality until proven otherwise.

引用

页数：4

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