Prevention of Staphylococcus epidermidis biofilm formation using electrical current

被引：11
作者：
Del Pozo, Jose L. [1 ,2 ]
Rouse, Mark S. [2 ]
Euba, Gorane [1 ,2 ]
Greenwood-Quaintance, Kerryl E. [2 ,4 ]
Mandrekar, Jayawant N. [3 ]
Steckelberg, James M. [1 ,2 ]
Patel, Robin [1 ,2 ,4 ]
机构：
[1] Mayo Clin, Coll Med, Div Infect Dis, Dept Med, Rochester, MN 55905 USA
[2] Mayo Clin, Coll Med, Infect Dis Res Lab, Rochester, MN 55905 USA
[3] Mayo Clin, Coll Med, Dept Hlth Sci Res, Rochester, MN 55905 USA
[4] Mayo Clin, Coll Med, Div Clin Microbiol, Dept Lab Med & Pathol, Rochester, MN 55905 USA
来源：
JOURNAL OF APPLIED BIOMATERIALS & FUNCTIONAL MATERIALS | 2014年 / 12卷 / 02期
关键词：
Electrical current; Staphylococcus epidermidis; Biofilm; Electricidal effect; CURRENT-INDUCED DETACHMENT; ANTIMICROBIAL AGENTS; BACTERIA;
D O I：
10.5301/jabfm.5000208
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
A technique for the prevention of staphylococcal adhesion by electrical current exposure was investigated. Teflon coupons were exposed to a continuous flow of 10(3) cfu/ml Staphylococcus epidermidis with or without 2000 microA DC electrical current delivered by electrodes on opposite sides of a coupon, touching neither each other nor the coupon. A mean 3.46 (SD, 0.20) and 5.70 (SD, 1.03) log(10) cfu/cm(2) were adhered to the non-electrical current exposed coupons after 4 h and 24 h, respectively. A mean 2.46 (SD, 0.31) and 1.47 (SD, 0.73) log(10) cfu/cm(2) were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by graphite electrodes. A mean 2.21 (SD, 0.14) and 0.55 (SD, 0.00) log(10) cfu/cm(2) were adhered after 4 h and 24 h with exposure to 2000 microA electrical current delivered by stainless steel electrodes. Electrical current may be useful in the prevention of staphylococcal adhesion to biomaterials.
引用
收藏
页码：81 / 83
页数：3
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