The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer

被引：102

作者：

McArdle, PA ^{[1
]}

Canna, K

McMillan, DC

McNicol, AM

Campbell, R

Underwood, MA

机构：

[1] Univ Glasgow, Royal Infirm, Dept Surg, Glasgow G31 2ER, Lanark, Scotland

[2] Univ Glasgow, Royal Infirm, Dept Pathol, Glasgow G31 2ER, Lanark, Scotland

[3] Univ Glasgow, Royal Infirm, Dept Urol, Glasgow G31 2ER, Lanark, Scotland

来源：

BRITISH JOURNAL OF CANCER | 2004年 / 91卷 / 03期

关键词：

CD4+; CD8+; T-lymphocytes; survival; prostate cancer;

D O I：

10.1038/sj.bjc.6601943

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The relationship between tumour stage, T-lymphocyte subset infiltration and survival was examined in patients with prostate cancer ( n = 80). On multivariate analysis PSA (HR 2.47, 95% CI 1.27 - 4.83, P = 0.008) and CD4+ T-lymphocyte count ( HR 2.29, 95% CI 1.25 - 4.22, P = 0.008) had independent significance. Increased CD4+ T-lymphocyte infiltration within the tumour was stage independent and associated with poor outcome in patients with prostate cancer.

引用

页码：541 / 543

页数：3

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