DOMINO: a database of domain-peptide interactions

被引:60
作者
Ceol, Arnaud [1 ]
Chatr-aryamontri, Andrew [1 ]
Santonico, Elena [1 ]
Sacco, Roberto [1 ]
Castagnoli, Luisa [1 ]
Cesareni, Gianni [1 ]
机构
[1] Univ Roma Tor Vergata, Dept Biol, I-00133 Rome, Italy
关键词
D O I
10.1093/nar/gkl961
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Many protein interactions are mediated by small protein modules binding to short linear peptides. DOMINO (http://mint.bio.uniroma2.it/domino/) is an open-access database comprising more than 3900 annotated experiments describing interactions mediated by protein-interaction domains. DOMINO can be searched with a versatile search tool and the interaction networks can be visualized with a convenient graphic display applet that explicitly identifies the domains/sites involved in the interactions.
引用
收藏
页码:D557 / D560
页数:4
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