The Effect of Borate Polymer Layers on Glucose Measurement by surface plasmon resonance

被引：0

作者：

Li, Dachao ^{[1
]}

Yang, Jia ^{[1
]}

Wu, Peng ^{[1
]}

Yang, Di ^{[1
]}

Wang, Bo ^{[2
]}

Lin, Yuan ^{[2
]}

Xu, Kexin ^{[1
]}

机构：

[1] Tianjin Univ, State Key Lab Precis Measuring Technol & Instrume, Tianjin 300072, Peoples R China

[2] Inst Appl Chem, Changchun, Peoples R China

来源：

ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC SYSTEMS XI | 2013年 / 8572卷

基金：

国家高技术研究发展计划(863计划); 中国博士后科学基金; 中国国家自然科学基金;

关键词：

glucose concentration; surface plasmon resonance; borate polymer; layer-by-layer binding;

D O I：

10.1117/12.2003508

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A new borate polymer PAA-ran-PAAPBA that can adsorb glucose specifically is introduced into the glucose measurement based on surface plasmon resonance. Six and twelve layers of borate polymer are bound onto the SPR sensors respectively through the layer-by-layer self-assembly binding method, and then the effect of different layers on the glucose concentration measurement is studied. The experiment is conducted in three concentration ranges, 1 similar to 10mg/dL, 10 similar to 100mg/dL and 100 similar to 1000mg/dL. The Results show that the performance of 12-layer-polymer sensor is better than that of the 6-layer-polymer sensor in the first two ranges, and the measuring result has no big difference in the range of 100 similar to 1000mg/d. It indicates that the enhancement of polymer layer on the surface of SPR sensor can dramatically improve the glucose measurement in the low concentration range.

引用

页数：9

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