CAR T therapy extends its reach to autoimmune diseases

被引：27

作者：

Baker, Daniel J. ^{[1
,2
,3
,4
]}

June, Carl H. ^{[1
,2
,3
]}

机构：

[1] Univ Penn, Ctr Cellular Immunotherapies, Perelman Sch Med, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Pathol & Lab Med, Perelman Sch Med, Philadelphia, PA 19104 USA

[3] Univ Penn, Parker Inst Canc Immunotherapy, Philadelphia, PA 19104 USA

[4] Univ Penn, Cardiovasc Inst, Perelman Sch Med, Dept Med, Philadelphia, PA 19104 USA

来源：

CELL | 2022年 / 185卷 / 24期

关键词：

D O I：

10.1016/j.cell.2022.10.026

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

CAR T therapy has revolutionized the treatment of hematologic cancers. In their recent Nature Medicine paper, Mackensen et al. report the use of CART cells to treat systemic lupus erythematosus in five patients. This provides enthusiasm to further explore CAR T therapy beyond oncology.

引用

页码：4471 / 4473

页数：3

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