Synthesis, characterization of mixed ligand palladium(II) complexes of triphenylphosphine and anilines and their enzyme inhibition studies against β-glucuronidase.: The crystal structure of trans-dichloro-(m-chloroaniline)(triphenylphosphine)palladium(II)

被引：16
作者：
Asma, Maliha
Badshah, Amin [1 ]
Ali, Saqib
Sohail, Manzar
Fettouhi, Mohammed
Ahmad, Saeed
Malik, Abdul
机构：
[1] Quaid I Azam Univ, Dept Chem, Islamabad, Pakistan
[2] King Fahd Univ Petr & Minerals, Dept Chem, Dhahran 31261, Saudi Arabia
[3] Univ Engn & Technol, Dept Chem, Lahore, Pakistan
[4] Univ Karachi, HEJ Res Inst Chem, Karachi 32, Pakistan
来源：
TRANSITION METAL CHEMISTRY | 2006年 / 31卷 / 04期
关键词：
D O I：
10.1007/s11243-006-0027-z
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A number of palladium(II) complexes with Ph3P and aromatic amines as ligands having the general formula [(Ph3P)Pd(Ph3P)(NH2R)Cl-2] {where R = Ph (1), m-ClC6H4 (2), p-ClC6H5 (3)} and [Pd(CH3NHPh)Cl-2] (4), have been synthesized and characterized by elemental analysis, IR, H-1 and C-13 NMR. The X-ray crystal structure of [(Ph3P)Pd(m-ClC6H4NH2)Cl-2]center dot CH2 Cl-2 (2) shows a distorted square planar environment around the Pd(II) ion with the P-Pd-N and Cl(1)-Pd-Cl(2) bond angles of 174.88(5)degrees and 176.77(2)degrees respectively. The complexes were screened for enzyme inhibition activity against beta-glucuronidase and found to be active.
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页码：556 / 559
页数：4
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