A new sesquiterpene ester inhibiting no production from the fruits of Celastrus orbiculatus

被引：7

作者：

Guo, Y. -Q. ^{[1
]}

Li, X.

Lee, J. -J.

Xu, J.

Li, N.

Meng, D. -L.

Wang, J. -H.

机构：

[1] Shenyang Pharmaceut Univ, Res Dep Nat Med, Shenyang 110016, Peoples R China

[2] Korea Res Inst Biosci & Biotechnol, Taejon 305600, South Korea

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2006年 / 8卷 / 08期

关键词：

1; beta; 2; 6; alpha; 13-tetraacetoxy-9; alpha-cinnamoyloxy-beta-dihydroagarofuran; sesquiterpene ester; Celastrus orbiculatus;

D O I：

10.1080/10286020412331286498

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new beta-dihydroagarofuran sesquiterpene ester, 1 beta, 2 beta, 6 alpha, 13-tetraacetoxy-9 alpha-cinnamoyloxy-beta-dihydroagarofuran (1), and the known compound 1 beta, 6 alpha, 13-triacetoxy-9 alpha-benzoyloxy-beta-dihydroagarofuran (2), have been isolated from the fruits of Celastrus orbiculatus Thunb. Their structures have been elucidated on the basis of spectroscopic methods. Compound 1 shows moderate activity of inhibiting LPS-induced nitric oxide production in murine macrophage RAW264.7 cells, with an IC50 of 55.4 mu M.

引用

页码：739 / 742

页数：4

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