Genitourinary manifestations of sickle cell disease

被引：5

作者：

Gebreselassie, Surafel ^{[1
,2
]}

Simmons, Matthew N. ^{[3
]}

Montague, Drogo K. ^{[4
,5
,6
]}

机构：

[1] Cleveland Clin Florida, Transplant Ctr, Weston, FL USA

[2] Case Western Reserve Univ, Lerner Coll Med, Cleveland Clin, Med, Cleveland, OH 44106 USA

[3] Urol Specialists Oregon, Bend, OR USA

[4] Cleveland Clin, Glickman Urol & Kidney Inst, Ctr Genitourinary Reconstruct, Dept Urol, Cleveland, OH 44195 USA

[5] Case Western Reserve Univ, Lerner Coll Med, Cleveland Clin, Surg, Cleveland, OH 44106 USA

[6] Amer Urol Assoc, Erectile Dysfunct Guideline Update Panel, Marlton, NJ USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2015年 / 82卷 / 10期

关键词：

RENAL MEDULLARY CARCINOMA; GLOMERULAR HYPERFILTRATION; RISK-FACTORS; PRIAPISM; PREVALENCE; ANEMIA; NEPHROPATHY; MANAGEMENT; CHILDREN; HYDROXYUREA;

D O I：

10.3949/ccjm.82a.14029

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Sickle cell disease is a common genetic disorder characterized by sickling of red blood cells under conditions of reduced oxygen tension. In turn, sickling leads to intravascular hemolysis and vaso-occlusive events with subsequent tissue ischemia-reperfusion injury affecting multiple organs, including the genitourinary system. Our review of the genitourinary manifestations of sickle cell disease focuses on sickle cell nephropathy, priapism, and other genitourinary complications such as papillary necrosis and renal medullary carcinoma.

引用

页码：679 / 683

页数：5

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