Antioxidant and antimicrobial activities of a purified polysaccharide from yerba mate (Ilex paraguariensis)

被引：82

作者：

Kungel, Pamela T. A. N. ^{[1
,2
]}

Correa, Vanesa G. ^{[1
,2
]}

Correa, Rubia C. G. ^{[1
,2
]}

Peralta, Rosely Aparecida ^{[3
]}

Sokovic, Marina ^{[4
]}

Calhelha, Ricardo C. ^{[5
]}

Bracht, Adelar ^{[1
,2
]}

Ferreira, Isabel C. F. R. ^{[5
]}

Peralta, Rosane M. ^{[1
,2
]}

机构：

[1] Univ Estadual Maringa, Dept Biochem, Maringa, Parana, Brazil

[2] Univ Estadual Maringa, Postgrad Program Food Sci, Maringa, Parana, Brazil

[3] Univ Fed Santa Catarina, Dept Chem, Florianopolis, SC, Brazil

[4] Univ Belgrade, Dept Plant Physiol, Inst Biol Res Sinisa Stankovic, Belgrade, Serbia

[5] Polytech Inst Braganca IPB, Mt Res Ctr CIMO, Campus Santa Apolonia, Braganca, Portugal

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2018年 / 114卷

关键词：

Antioxidant activity; Antimicrobial activity; Polysaccharide; Yerba mate; EXTRACTION OPTIMIZATION; RHAMNOGALACTURONAN-I; BIOACTIVE PROPERTIES; ST HIL; TEA; LEAF; PHYTOCHEMICALS; PURIFICATION; STABILITY; DIGESTION;

D O I：

10.1016/j.ijbiomac.2018.04.020

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This study investigated the antioxidant, antimicrobial and cytotoxic properties of a purified yerba mate polysaccharide. The yerba mate polysaccharide showed a prominent antioxidant activity as evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH center dot)-radical scavenging activity (IC50 = 1.25 +/- 0.10 mg/mL), 3-ethyl benzothiazoline-6-sulphonic acid (ABTS center dot+)-radical scavenging activity (IC50 = 0.41 +/- 0.05 mg/mL), and hydroxyl scavenging activity (IC50 = 3.36 +/- 0.31 mg/mL). The antioxidant activity evaluated as the ferric ion reduction power (FRAP) and oxygen radical absorbance radical assay (ORAC), expressed as trolox equivalents, were 20.84 +/- 1.61 mu M TE/mg and 55630 +/- 12.83 mu M TE/mg, respectively. The purified yerba mate polysaccharide presented high antimicrobial activity against several bacterial and fungal strains; however, no cytotoxicity against all four tumor human cell lines assessed. (C) 2018 Elsevier B.V. All rights reserved.

引用

页码：1161 / 1167

页数：7

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