Different-sized black phosphorus nanosheets with good cytocompatibility and high photothermal performance

被引:73
作者
Fu, Haidi [1 ,2 ,3 ]
Li, Zhibin [3 ,4 ]
Xie, Hanhan [3 ]
Sun, Zhengbo [3 ]
Wang, Beike [1 ,2 ]
Huang, Hao [3 ]
Han, Guangli [1 ,2 ]
Wang, Huaiyu [3 ]
Chu, Paul K. [4 ]
Yu, Xue-Feng [3 ]
机构
[1] Wuhan Univ, State Key Lab Breeding Base Basic Sci Stomatol Hu, Key Lab Oral Biomedicine Minist Educ KLOBM, 237 Luoyu Rd, Wuhan 430079, Peoples R China
[2] Wuhan Univ, Dept Orthodont, Sch & Hosp Stomatol, 237 Luoyu Rd, Wuhan 430079, Peoples R China
[3] Chinese Acad Sci, Shenzhen Inst Adv Technol, Inst Biomed & Biotechnol, Shenzhen 518055, Peoples R China
[4] City Univ Hong Kong, Dept Phys & Mat Sci, Tat Chee Ave, Kowloon, Hong Kong, Peoples R China
来源
RSC ADVANCES | 2017年 / 7卷 / 24期
基金
中国国家自然科学基金;
关键词
FIELD-EFFECT TRANSISTORS; GRAPHENE OXIDE; SOLAR-CELLS; LAYER; THERAPY; NANOPARTICLES; EXFOLIATION; STABILITY; BATTERIES; RESPONSES;
D O I
10.1039/c7ra00160f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
As a new kind of two-dimensional (2D) material, black phosphorus (BP) has attracted explosive interest in biomedical applications. It is well-recognized that the biomedical performances of nanoparticles depend not only on their properties, but also on their structures and dimensions. Here in this study, we successfully prepared three kinds of BP nanosheets with different sizes, then systematically investigated their cytocompatibility and photothermal effects to ablate cancer cells. It is evident from various assays that all the three BP samples have excellent cytocompatibility, and the BP nanosheets with a large size have better photothermal efficiency for cancer cell ablation. Our findings may provide a new insight into the fundamental cyto-performances of BP.
引用
收藏
页码:14618 / 14624
页数:7
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