Xanthones from Hypericum roeperanum

被引：111

作者：

Rath, G

Potterat, O

Mavi, S

Hostettmann, K

机构：

[1] UNIV LAUSANNE, INST PHARMACOGNOSIE & PHYTOCHIM, BEP, CH-1015 LAUSANNE, SWITZERLAND

[2] NATL HERBARIUM, CAUSEWAY, ZIMBABWE

[3] NATL BOT GARDEN, CAUSEWAY, ZIMBABWE

来源：

PHYTOCHEMISTRY | 1996年 / 43卷 / 02期

关键词：

Hypericum roeperanum; Guttiferae; xanthones; 1,6-dihydroxy-5-methoxy-4',5'-dihydro-4',4',5'-trimethylfurano-(2',3':3,4)-xanthone; 1,6-dihydroxy-5-methoxy-6',6'dimethylpyrano-(2',3':3,4)-xanthone; 1,3,5,6-tetrahydroxy-2-(2',2'-dimethyl-4'-isopropenyl)-cyclopentanyl-xanthone; 1,3,5,6-tetrahydroxy-4-trans-sesquilavandulylxanthone; roeperanone; antifungal activity;

D O I：

10.1016/0031-9422(96)00284-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four new xanthones have been isolated from the roots of Hypericum roeperanum. Their structures have been established by a combination of spectroscopic and chemical methods as 1,6-dihydroxy-5-methoxy-4',5'-dihydro-4',4',5'-trimethylfurano- (2',3':3,4)-xanthone (5-O-methyl-2-deprenylrheediaxanthone B), 1,6-dihydroxy 5-methoxy-6',6'-dimethylpyrano-(2',3':3,4)-xanthone (5-O-methylisojacareubin), 1,3,5,6-tetrahydroxy-2-(2',2'-dimethyl-4'-isopropenyl)- cyclopentanylxanthone (5-O-demethylpaxanthonin) and 1,3,5,6-tetrahydroxy-4-trans-sesquilavandulylxanthone (roeperanone). In addition, 2-hydroxyxanthone, 5-hydroxy-2-methoxyxanthone, 1,5-dihydroxy-2-methoxyxanthone, 2-deprenyl rheediaxanthone B, isojacareubin and calycinoxanthone D have been isolated and characterized. Some of the isolated xanthones exhibited antifungal activity against Candida albicans. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：513 / 520

页数：8

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