Role of DNA polyrnerase IV in Escherichia coli SOS mutator activity

被引：31
作者：
Kuban, Wojciech
Banach-Orlowska, Magdalena
Schaaper, Roel M.
Jonczyk, Piotr
Fijalkowska, Iwona J.
机构：
[1] Polish Acad Sci, Inst Biochem & Biophys, PL-02106 Warsaw, Poland
[2] NIEHS, Mol Genet Lab, Res Triangle Pk, NC 27709 USA
来源：
JOURNAL OF BACTERIOLOGY | 2006年 / 188卷 / 22期
关键词：
POLYMERASE-III HOLOENZYME; POL-IV; ADAPTIVE MUTATION; LAGGING-STRAND; RECA PROTEIN; UNTARGETED MUTAGENESIS; GENETIC REQUIREMENTS; BASE SUBSTITUTION; FIDELITY; REPLICATION;
D O I：
10.1128/JB.01088-06
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Constitutive expression of the SOS regulon in Escherichia coli recA730 strains leads to a mutator phenotype (SOS mutator) that is dependent on DNA polymerase V (umuDC gene product). Here we show that a significant fraction of this effect also requires DNA polymerase IV (dinB gene product).
引用
收藏
页码：7977 / 7980
页数：4
相关论文
共 46 条
12345