Fabrication of Monodisperse Toroidal Particles by Polymer Solidification in Microfluidics

被引:83
作者
Wang, Baoguo [1 ,2 ]
Shum, Ho Cheung [1 ]
Weitz, David A. [1 ,3 ]
机构
[1] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA
[2] Tsinghua Univ, Dept Chem Engn, Beijing 100084, Peoples R China
[3] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
基金
美国国家科学基金会;
关键词
colloids; composites; emulsions; particles; polymers; PHASE-SEPARATION; SHAPE; SIZE; MICROPARTICLES; COPOLYMERS; EMULSIONS; DOUGHNUTS; REACTORS; DESIGN;
D O I
10.1002/cphc.200800786
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
(Figure Presented) Microdoughnuts: Polymer toroidal particles such as the one shown in the left picture have been prepared by a capillary microfluidic technique. Droplets of polymer solution undergo non-uniform solidification to form the anisotropic polymer particles. By incorporating functional materials inside the polymer network, functional toroidal particles (center and right images) can be tailormade for specific applications such as magnetic actuation. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:641 / 645
页数:5
相关论文
共 34 条
[1]   Glass coating for PDMS microfluidic channels by sol-gel methods [J].
Abate, Adam R. ;
Lee, Daeyeon ;
Do, Thao ;
Holtze, Christian ;
Weitz, David A. .
LAB ON A CHIP, 2008, 8 (04) :516-518
[2]   Dunking doughnuts into cells -: selective cellular translocation and in vivo analysis of polymeric micro-doughnuts [J].
Alexander, Lois ;
Dhaliwal, Kevin ;
Simpson, John ;
Bradley, Mark .
CHEMICAL COMMUNICATIONS, 2008, (30) :3507-3509
[3]  
[Anonymous], 2005, ANGEW CHEM, DOI DOI 10.1002/ANGE.200462226
[4]   Role of target geometry in phagocytosis [J].
Champion, JA ;
Mitragotri, S .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (13) :4930-4934
[5]   Particle shape: A new design parameter for micro- and nanoscale drug delivery carriers [J].
Champion, Julie A. ;
Katare, Yogesh K. ;
Mitragotri, Samir .
JOURNAL OF CONTROLLED RELEASE, 2007, 121 (1-2) :3-9
[6]   Controllable monodisperse multiple emulsions [J].
Chu, Liang-Yin ;
Utada, Andrew S. ;
Shah, Rhutesh K. ;
Kim, Jin-Woong ;
Weitz, David A. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (47) :8970-8974
[7]   Monodisperse thermoresponsive microgels with tunable volume-phase transition kinetics [J].
Chu, Liang-Yin ;
Kim, Jin-Woong ;
Shah, Rhutesh K. ;
Weitz, David A. .
ADVANCED FUNCTIONAL MATERIALS, 2007, 17 (17) :3499-3504
[8]   Honeycomb coated particles: porous doughnuts, golf balls and hollow porous pockets [J].
Connal, Luke A. ;
Qiao, Greg G. .
SOFT MATTER, 2007, 3 (07) :837-839
[9]   Block copolymer assembly via kinetic control [J].
Cui, Honggang ;
Chen, Zhiyun ;
Zhong, Sheng ;
Wooley, Karen L. ;
Pochan, Darrin J. .
SCIENCE, 2007, 317 (5838) :647-650
[10]   Polymersomes: Tough vesicles made from diblock copolymers [J].
Discher, BM ;
Won, YY ;
Ege, DS ;
Lee, JCM ;
Bates, FS ;
Discher, DE ;
Hammer, DA .
SCIENCE, 1999, 284 (5417) :1143-1146