Two Episodes of Transfusion-related Acute Lung Injury (TRALI) Occurring within a Short Period

被引：3

作者：

Akagi, Yuina ^{[1
]}

Murata, Shogo ^{[1
]}

Yamashita, Yusuke ^{[1
]}

Tanaka, Ken ^{[1
]}

Hiroi, Takayuki ^{[1
]}

Mushino, Toshiki ^{[1
]}

Hosoi, Hiroki ^{[1
]}

Nishikawa, Akinori ^{[1
]}

Tamura, Shinobu ^{[1
]}

Sonoki, Takashi ^{[1
]}

机构：

[1] Wakayama Med Univ, Dept Hematol Oncol, Wakayama, Japan

来源：

INTERNAL MEDICINE | 2020年 / 59卷 / 20期

关键词：

transfusion-related acute lung injury; two TRALI episodes; non-antibody-mediated TRALI; platelet transfusion; PATHOGENESIS; RISK;

D O I：

10.2169/internalmedicine.4700-20

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Transfusion-related acute lung injury (TRALI) is a non-hemolytic adverse reaction that occurs 5 6 hours after receiving a transfusion. A 72-year-old man with leukemia developed severe hypoxemia after platelet transfusions on two occasions within a 4-day period. During the first episode, the transfused platelet preparation was positive for anti-human-leukocyte antigen antibodies. The pathogenesis of TRALI includes an antibody-mediated mechanism and a non-antibody-mediated mechanism, in which various factors combine to activate pulmonary neutrophils. In our case, it is considered that the patient's neutrophils reached the activation threshold for the development of TRALI after the accumulation of various factors besides anti-leukocyte antibodies.

引用

页码：2577 / 2581

页数：5

共 17 条

[1] Transfusion-related acute lung injury due to HLA-A2-specific antibodies in recipient and NB1-specific antibodies in donor blood [J].

Bux, J ;

Becker, F ;

Seeger, W ;

Kilpatrick, D ;

Chapman, J ;

Waters, A .

BRITISH JOURNAL OF HAEMATOLOGY, 1996, 93 (03) :707-713

[2] The pathogenesis of transfusion-related acute lung injury (TRALI) [J].

Bux, Jurgen ;

Sachs, Ulrich J. H. .

BRITISH JOURNAL OF HAEMATOLOGY, 2007, 136 (06) :788-799

[3] Effective reduction of transfusion-related acute lung injury risk with male-predominant plasma strategy in the American Red Cross (2006-2008) [J].

Eder, Anne F. ;

Herron, Ross M., Jr. ;

Strupp, Annie ;

Dy, Beth ;

White, Jenni ;

Notari, Edward P. ;

Dodd, Roger Y. ;

Benjamin, Richard J. .

TRANSFUSION, 2010, 50 (08) :1732-1742

[4] Current understanding of allergic transfusion reactions: incidence, pathogenesis, laboratory tests, prevention and treatment [J].

Hirayama, Fumiya .

BRITISH JOURNAL OF HAEMATOLOGY, 2013, 160 (04) :434-444

[5] Toward an understanding of transfusion-related acute lung injury: statement of a consensus panel [J].

Kleinman, S ;

Caulfield, T ;

Chan, P ;

Davenport, R ;

McFarland, I ;

McPhedran, S ;

Meade, M ;

Morrison, D ;

Pinsent, T ;

Robillard, P ;

Slinger, P .

TRANSFUSION, 2004, 44 (12) :1774-1789

[6] Transfusion-related acute lung injury not a two-hit, but a multicausal model [J].

Middelburg, Rutger A. ;

van der Bom, Johanna G. .

TRANSFUSION, 2015, 55 (05) :953-960

[7] Transfusion-related acute lung injury (TRALI): Clinical presentation, treatment, and prognosis [J].

Moore, SB .

CRITICAL CARE MEDICINE, 2006, 34 (05) :S114-S117

[8] Pathogenesis of non-antibody mediated transfusion-related acute lung injury from bench to bedside [J].

Peters, Anna L. ;

van Hezel, Maike E. ;

Juffermans, Nicole P. ;

Vlaar, Alexander P. J. .

BLOOD REVIEWS, 2015, 29 (01) :51-61

[9] DIAGNOSTIC AND PATHOGENETIC CONSIDERATIONS IN TRANSFUSION-RELATED ACUTE LUNG INJURY [J].

POPOVSKY, MA ;

MOORE, SB .

TRANSFUSION, 1985, 25 (06) :573-577

[10] Transfusion-associated circulatory overload and transfusion-related acute lung injury [J].

Semple, John W. ;

Rebetz, Johan ;

Kapur, Rick .

BLOOD, 2019, 133 (17) :1840-1853

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