PROCALCITONIN AS A BIOMARKER OF THE EARLY STAGE OF BACTERIAL INFECTIONS IN HIV/AIDS PATIENTS

被引：0

作者：

Mikula, T. ^{[1
]}

Suchacz, M. ^{[1
]}

Stanczak, W. ^{[1
]}

Kozlowska, J. ^{[1
]}

Wiercinska-Drapalo, A. ^{[1
]}

机构：

[1] Med Univ Warsaw, Dept Hepatol & Acquired Immunodeficiences, PL-01201 Warsaw, Poland

来源：

EUROPEAN JOURNAL OF INFLAMMATION | 2014年 / 12卷 / 02期

关键词：

HIV/AIDS; PCT; CRP; bacterial infection; C-REACTIVE PROTEIN; SEPSIS; BACTEREMIA; DIAGNOSIS; MARKER; ADULTS;

D O I：

10.1177/1721727X1401200210

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We observed that low concentrations of procalcitonin (PCT) in the early stages of bacterial infection among HIV/AIDS patients are not always associated with a good prognosis. Many of our patients developed sepsis despite a PCT level of <0.5 ng/ml on the first days of infection. The aim of our study was to assess whether laboratory standards for PCT in patients with HIV/AIDS correlate with their clinical condition. We analyzed the concentration of PCT and other inflammatory markers in the early stages of bacterial infection among 40 HIV-infected patients and 52 AIDS patients enrolled for the study. The control group consisted of 37 healthy individuals. In comparison with PCT and WBC, PCT proved to be the most reliable in the early stages of bacterial infection. To conclude, we suggest new PCT cut-off ranges for HIV/AIDS patients with bacterial infection.

引用

页码：305 / 313

页数：9

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