Diffuse Renal Parenchyma Uptake With Bone Scintigraphy in a Patient With Paroxysmal Nocturnal Hemoglobinuria and Normal Kidney Function

被引:4
作者
Balink, Hans [1 ]
Hoogendoorn, Mels [2 ]
Hemmelder, Marc [3 ]
机构
[1] Med Ctr Leeuwarden, Dept Nucl Med, NL-8901 BR Leeuwarden, Netherlands
[2] Med Ctr Leeuwarden, Dept Hematol, NL-8901 BR Leeuwarden, Netherlands
[3] Med Ctr Leeuwarden, Dept Nephrol, NL-8901 BR Leeuwarden, Netherlands
关键词
Tc-99m-HDP; bone scintigraphy; paroxysmal nocturnal hemoglobinuria; increased renal parenchyma uptake;
D O I
10.1097/RLU.0000000000000333
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A 41-year-old woman with a Harrington spondylodesis presented with lower back pain. Bone scintigraphy showed diffusely increased parenchymal uptake in both kidneys. She reported 2 previous periods of dark, almost black, urine. Additional flow cytometric analysis confirmed the diagnosis of paroxysmal nocturnal hemoglobinuria. The increased renal parenchyma uptake is very probably due to paroxysmal nocturnal hemoglobinuriaYrelated renal hemosiderosis. Remarkably, the patient did not develop any abnormality of renal function. Copyright © 2014 by Lippincott Williams & Wilkins.
引用
收藏
页码:274 / 276
页数:3
相关论文
共 8 条
[1]   EVALUATION OF INTENSE RENAL PARENCHYMAL ACTIVITY (HOT KIDNEYS) ON BONE-SCINTIGRAPHY [J].
BERNARD, MS ;
HAYWARD, M ;
HAYWARD, C ;
MUNDY, L .
CLINICAL NUCLEAR MEDICINE, 1990, 15 (04) :254-256
[2]  
Brodsky A, 2012, EXP HEMATOL ONCOL, V1, DOI 10.1186/2162-3619-1-26
[3]   Reversible renal failure in paroxysmal nocturnal hemoglobinuria [J].
Chow, KM ;
Lai, FMM ;
Wang, AYM ;
Chan, YL ;
Tang, NLS ;
Li, PKT .
AMERICAN JOURNAL OF KIDNEY DISEASES, 2001, 37 (02)
[4]   The Role of Bone SPECT/CT in the Evaluation of Lumbar Spinal Fusion With Metallic Fixation Devices [J].
Damgaard, Morten ;
Nimb, Lars ;
Madsen, Jan L. .
CLINICAL NUCLEAR MEDICINE, 2010, 35 (04) :234-236
[5]   NATURAL-HISTORY OF PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA [J].
HILLMEN, P ;
LEWIS, SM ;
BESSLER, M ;
LUZZATTO, L ;
DACIE, JV .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (19) :1253-1258
[6]   Diagnosis and management of paroxysmal nocturnal hemoglobinuria [J].
Parker, C ;
Omine, M ;
Richards, S ;
Nishimura, J ;
Bessler, M ;
Ware, R ;
Hillmen, P ;
Luzzatto, L ;
Young, N ;
Kinoshita, T ;
Rosse, W ;
Socié, G .
BLOOD, 2005, 106 (12) :3699-3709
[7]   ABNORMAL TC-99M MDP RENAL IMAGES ASSOCIATED WITH MYOGLOBINURIA [J].
STY, JR ;
STARSHAK, RJ .
CLINICAL NUCLEAR MEDICINE, 1982, 7 (10) :476-476
[8]   Thrombosis in Patients with Paroxysmal Nocturnal Hemoglobinuria [J].
Weitz, Ilene C. .
SEMINARS IN THROMBOSIS AND HEMOSTASIS, 2011, 37 (03) :315-321