FDG-PET in radiotherapy treatment planning of advanced head and neck cancer -: A prospective clinical analysis

被引：8
|
作者：
Dietl, Barbara
Marienhagen, Jorg
Kuehnel, Thomas
Schaefer, Christof
Koelbl, Oliver
机构：
[1] Univ Regensburg, Dept Radiat Therapy, D-93053 Regensburg, Germany
[2] Univ Regensburg, Dept Nucl Med, D-93053 Regensburg, Germany
[3] Univ Regensburg, Dept Otorhinolaryngol, D-93053 Regensburg, Germany
来源：
AURIS NASUS LARYNX | 2006年 / 33卷 / 03期
关键词：
FDG-PET; diagnostic impact; therapeutic impact; head and neck cancer; radiotherapy treatment planning;
D O I：
10.1016/j.anl.2006.01.002
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Background: A prospective clinical analysis was carried out to assess the diagnostic and therapeutic impact of fluorodeoxyglucose positron emission tomography (FDG-PET) on planning radiotherapy in patients with advanced head and neck cancer in AJCC Stages III/IV. Methods: From July 1999 to May 2004 FDG-PET was performed in 49 patients prior to radiotherapy for exclusion of systemic disease, synchronous second or unknown primary tumors. Results: 45/49 (91.9%) FDG-PET findings could be confirmed in comparison with conventional imaging and the clinical follow up of 9.5 months. 21/49 FDG-PET (42.8%) yielded new diagnostic information with therapeutic implications in 20/49 (40.8%) cases. The therapy strategy was changed in 14/49 patients, minor modifications in the portal design occurred in 6/49 patients. 9/49 (18.3%) FDG-PET supported a curative strategy, 11/49 (22.4%) a palliative one. Conclusions: FDG-PET is a useful and important diagnostic tool mainly for exclusion of systemic disease in advanced head and neck cancer, thus influencing radiotherapy in 20/49 (40.8%) of patients investigated in our study. (C) 2006 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：303 / 309
页数：7
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