Complexity in simplicity: monogenic disorders and complex cardiomyopathies

被引:74
作者
Chen, J
Chien, KR [1 ]
机构
[1] Univ Calif San Diego, Dept Med, Salk NHLBI Program Mol Med, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Sch Med, Ctr Mol Genet, La Jolla, CA 92093 USA
关键词
D O I
10.1172/JCI7297
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:1483 / 1485
页数:3
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共 16 条
[11]   Disruption of muscle architecture and myocardial degeneration in mice lacking desmin [J].
Milner, DJ ;
Weitzer, G ;
Tran, D ;
Bradley, A ;
Capetanaki, Y .
JOURNAL OF CELL BIOLOGY, 1996, 134 (05) :1255-1270
[12]   α-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy [J].
Mogensen, J ;
Klausen, IC ;
Pedersen, AK ;
Egeblad, H ;
Bross, P ;
Kruse, TA ;
Gregersen, N ;
Hansen, PS ;
Baandrup, U ;
Borglum, AD .
JOURNAL OF CLINICAL INVESTIGATION, 1999, 103 (10) :R39-R43
[13]   Actin mutations in dilated cardiomyopathy, a heritable form of heart failure [J].
Olson, TM ;
Michels, VV ;
Thibodeau, SN ;
Tai, YS ;
Keating, MT .
SCIENCE, 1998, 280 (5364) :750-752
[14]   Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, delta-sarcoglycan, in hamster: An animal model of disrupted dystrophin-associated glycoprotein complex [J].
Sakamoto, A ;
Ono, K ;
Abe, M ;
Jasmin, G ;
Eki, T ;
Murakami, Y ;
Masaki, T ;
Toyooka, T ;
Hanaoka, F .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (25) :13873-13878
[15]  
SEIDMAN CE, 1999, MOL BASIS CARDIOVASC, P251
[16]   The role of cytoskeletal proteins in cardiomyopathies [J].
Towbin, JA .
CURRENT OPINION IN CELL BIOLOGY, 1998, 10 (01) :131-139