Complexity in simplicity: monogenic disorders and complex cardiomyopathies

被引：74
作者：
Chen, J
Chien, KR [1 ]
机构：
[1] Univ Calif San Diego, Dept Med, Salk NHLBI Program Mol Med, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Sch Med, Ctr Mol Genet, La Jolla, CA 92093 USA
来源：
JOURNAL OF CLINICAL INVESTIGATION | 1999年 / 103卷 / 11期
关键词：
D O I：
10.1172/JCI7297
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：1483 / 1485
页数：3
相关论文
共 16 条
[1]   MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure [J].
Arber, S ;
Hunter, JJ ;
Ross, J ;
Hongo, M ;
Sansig, G ;
Borg, J ;
Perriard, JC ;
Chien, KR ;
Caroni, P .
CELL, 1997, 88 (03) :393-403
[2]   Enteroviral protease 2A cleaves dystrophin: Evidence of cytoskeletal disruption in an acquired cardiomyopathy [J].
Badorff, C ;
Lee, GH ;
Lamphear, BJ ;
Martone, ME ;
Campbell, KP ;
Rhoads, RE ;
Knowlton, KU .
NATURE MEDICINE, 1999, 5 (03) :320-326
[3]   Familial hypertrophic cardiomyopathy from mutations to functional defects [J].
Bonne, G ;
Carrier, L ;
Richard, P ;
Hainque, B ;
Schwartz, K .
CIRCULATION RESEARCH, 1998, 83 (06) :580-593
[4]   3 MUSCULAR-DYSTROPHIES - LOSS OF CYTOSKELETON EXTRACELLULAR-MATRIX LINKAGE [J].
CAMPBELL, KP .
CELL, 1995, 80 (05) :675-679
[5]  
Chen J, 1998, DEVELOPMENT, V125, P1943
[6]   γ-Sarcoglycan deficiency leads to muscle membrane defects and apoptosis independent of dystrophin [J].
Hack, AA ;
Ly, CT ;
Jiang, F ;
Clendenin, CJ ;
Sigrist, KS ;
Wollmann, RL ;
McNally, EM .
JOURNAL OF CELL BIOLOGY, 1998, 142 (05) :1279-1287
[7]   Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress [J].
Hirota, H ;
Chen, J ;
Betz, UAK ;
Rajewsky, K ;
Gu, Y ;
Ross, J ;
Müller, W ;
Chien, KR .
CELL, 1999, 97 (02) :189-198
[8]  
HUNTER JJ, 1999, IN PRESS N ENGL J ME
[9]   Cardiovascular lesions and skeletal myopathy in mice lacking desmin [J].
Li, ZL ;
ColucciGuyon, E ;
PinconRaymond, M ;
Mericskay, M ;
Pournin, S ;
Paulin, D ;
Babinet, C .
DEVELOPMENTAL BIOLOGY, 1996, 175 (02) :362-366
[10]   Molecular heterogeneity in very-long-chain acyl-CoA dehydrogenase deficiency causing pediatric cardiomyopathy and sudden death [J].
Mathur, A ;
Sims, HF ;
Gopalakrishnan, D ;
Gibson, B ;
Rinaldo, P ;
Vockley, J ;
Hug, G ;
Strauss, AW .
CIRCULATION, 1999, 99 (10) :1337-1343
12