Plasma modification of polytetrafluoroethylene for immobilization of the fibrinolytic protein urokinase

被引：23

作者：

König, U ^{[1
]}

Nitschke, M ^{[1
]}

Menning, A ^{[1
]}

Sperling, C ^{[1
]}

Simon, F ^{[1
]}

Arnhold, C ^{[1
]}

Werner, C ^{[1
]}

Jacobasch, HJ ^{[1
]}

机构：

[1] Inst Polymer Res Dresden, D-01069 Dresden, Germany

来源：

SURFACE & COATINGS TECHNOLOGY | 1999年 / 116卷

关键词：

grafting; immobilization; plasma modification; polytetrafluoroethylene; urokinase;

D O I：

10.1016/S0257-8972(99)00258-3

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The modification of surface properties is necessary to improve the blood compatibility of polytetrafluoroethylene (PTFE). This paper describes the concept of a modification of PTFE surfaces. It consists of three steps: first, water vapour microwave plasma modification: second. acrylic acid vapour-phase post-grafting; and third; immobilization of the fibrinolytic protein urokinase. During or after each step, the modification results were characterized by zeta potential, ellipsometry, wetting measurements and S-ray photoelectron spectroscopy. (C) 1999 Elsevier Science S.A. All rights reserved.

引用

页码：1011 / 1015

页数：5

共 14 条

[1]

BEAMSON G, 1992, SIENTA ESCA 300 DATA

[2] IMMOBILIZATION OF ACTIVE UROKINASE ON ALBUMIN MICROSPHERES - USE OF A CHEMICAL DEHYDRANT AND PROCESS MONITORING [J].