The role of aquatic ecosystems as reservoirs of antibiotic resistance

被引:527
作者
Marti, Elisabet [1 ]
Variatza, Eleni [1 ]
Luis Balcazar, Jose [1 ]
机构
[1] Univ Girona, Catalan Inst Water Res ICRA, Girona 17003, Spain
关键词
aquatic environments; bacteria; antibiotic resistance; antibiotic resistance genes; mobile genetic elements; bacteriophages; MOBILE GENETIC ELEMENTS; ESCHERICHIA-COLI; WASTE-WATER; ANTIMICROBIAL RESISTANCE; BETA-LACTAMASES; KLUYVERA-ASCORBATA; SOIL BACTERIA; PLASMID; ENVIRONMENT; HEALTH;
D O I
10.1016/j.tim.2013.11.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Although antibiotic resistance has become a major threat to human health worldwide, this phenomenon has been largely overlooked in studies in environmental settings. Aquatic environments may provide an ideal setting for the acquisition and dissemination of antibiotic resistance, because they are frequently impacted by anthropogenic activities. This review focuses primarily on the emergence and dissemination of antibiotic resistance in the aquatic environment, with a special emphasis' on the role of antibiotic resistance genes.
引用
收藏
页码:36 / 41
页数:6
相关论文
共 62 条
[1]  
Aarestrup F.M., 2005, ANTIMICROBIAL RESIST
[2]   Veterinary drug usage and antimicrobial resistance in bacteria of animal origin [J].
Aarestrup, FM .
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2005, 96 (04) :271-281
[3]   Molecular mechanisms of antibacterial multidrug resistance [J].
Alekshun, Michael N. ;
Levy, Stuart B. .
CELL, 2007, 128 (06) :1037-1050
[4]   Functional metagenomics reveals diverse β-lactamases in a remote Alaskan soil [J].
Allen, Heather K. ;
Moe, Luke A. ;
Rodbumrer, Jitsupang ;
Gaarder, Andra ;
Handelsman, Jo .
ISME JOURNAL, 2009, 3 (02) :243-251
[5]   Heavy use of prophylactic antibiotics in aquaculture: a growing problem for human and animal health and for the environment [J].
Cabello, Felipe C. .
ENVIRONMENTAL MICROBIOLOGY, 2006, 8 (07) :1137-1144
[6]   Differentiating anthropogenic impacts on ARGs in the Pearl River Estuary by using suitable gene indicators [J].
Chen, Baowei ;
Liang, Ximei ;
Huang, Xiaoping ;
Zhang, Tong ;
Li, Xiangdong .
WATER RESEARCH, 2013, 47 (08) :2811-2820
[7]   Antibiotic Resistance Genes in the Bacteriophage DNA Fraction of Environmental Samples [J].
Colomer-Lluch, Marta ;
Jofre, Juan ;
Muniesa, Maite .
PLOS ONE, 2011, 6 (03)
[8]   The relationship between antimicrobial resistance and patient outcomes: Mortality, length of hospital stay, and health care costs [J].
Cosgrove, SE .
CLINICAL INFECTIOUS DISEASES, 2006, 42 :S82-S89
[9]   Broad Dissemination of Plasmid-Mediated Quinolone Resistance Genes in Sediments of Two Urban Coastal Wetlands [J].
Cummings, David E. ;
Archer, Karisa F. ;
Arriola, David J. ;
Baker, Pieter A. ;
Faucett, K. Grace ;
Laroya, Jonathan B. ;
Pfeil, Kelly L. ;
Ryan, Cody R. ;
Ryan, Kelsey R. U. ;
Zuill, Douglas E. .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2011, 45 (02) :447-454
[10]   Extended spectrum β-lactamases, carbapenemases and mobile genetic elements responsible for antibiotics resistance in Gram-negative bacteria [J].
El Salabi, Allaaeddin ;
Walsh, Timothey R. ;
Chouchani, Chedly .
CRITICAL REVIEWS IN MICROBIOLOGY, 2013, 39 (02) :113-122