Targeting constitutively active STAT3 in chronic lymphocytic leukemia: A clinical trial of the STAT3 inhibitor pyrimethamine with pharmacodynamic analyses

被引:19
作者
Brown, Jennifer R. [1 ,2 ,3 ]
Walker, Sarah R. [1 ,2 ,3 ]
Heppler, Lisa N. [1 ]
Tyekucheva, Svitlana [4 ]
Nelson, Erik A. [1 ,2 ,3 ]
Klitgaard, Josephine [1 ]
Nicolais, Maria [1 ]
Kroll, Yasmin [1 ]
Xiang, Michael [1 ]
Yeh, Jennifer E. [1 ]
Chaudhury, Mousumi [1 ]
Giaccone, Zachary T. [1 ]
Fernandes, Stacey M. [1 ]
Jacobsen, Eric D. [1 ,2 ,3 ]
Fisher, David C. [1 ,2 ,3 ]
Freedman, Arnold S. [1 ,2 ,3 ]
Davids, Matthew S. [1 ,2 ,3 ]
Supko, Jeffrey G. [5 ]
Wu, Catherine [1 ,2 ,3 ]
Frank, David A. [1 ,2 ,3 ]
机构
[1] Dana Farber Canc Inst, Dept Med Oncol, 450 Brookline Ave,Mayer 522B, Boston, MA 02215 USA
[2] Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA 02115 USA
[3] Harvard Med Sch, Dept Med, Boston, MA 02115 USA
[4] Dana Farber Canc Inst, Dept Data Sci, Boston, MA 02115 USA
[5] Harvard Med Sch, Dept Med, Massachusetts Gen Hosp, Boston, MA 02115 USA
关键词
TRANSCRIPTION;
D O I
10.1002/ajh.26084
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E95 / E98
页数:4
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