Acquired Bleeding Disorders

被引:7
作者
Hurwitz, Alisheba [1 ]
Massone, Richard [1 ]
Lopez, Bernard L. [1 ]
机构
[1] Thomas Jefferson Univ Hosp, Dept Emergency Med, Philadelphia, PA 19107 USA
关键词
Bleeding Thrombocytopenia; Coagulopathy; Anticoagulant; Hemorrhage; Hemostasis; Transfusion; Emergency; PROTHROMBIN COMPLEX CONCENTRATE; THROMBOTIC THROMBOCYTOPENIC PURPURA; ACTIVATED FACTOR-VII; RECOMBINANT FACTOR VIIA; VITAMIN-K ANTAGONISTS; ED AMERICAN-COLLEGE; FACTOR XA INHIBITOR; EMERGENCY-DEPARTMENT; ACUTE COAGULOPATHY; TRANEXAMIC ACID;
D O I
10.1016/j.emc.2014.04.010
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Emergency medicine practitioners treat bleeding patients on a regular basis. Disorders of hemostasis are an additional challenge in these patients but can be assessed and managed in a systematic fashion. Of particular importance to the emergency clinician are the iatrogenic causes of abnormal hemostasis. Other acquired causes of abnormal hemostasis include renal disease, immune thrombocytopenia, thrombotic thrombocytopenic purpura, hemolytic uremic syndrome, acquired coagulation factor inhibitors, acute traumatic coagulopathy, liver disease, and disseminated intravascular coagulopathy.
引用
收藏
页码:691 / +
页数:25
相关论文
共 119 条
  • [1] Oral Anticoagulant Therapy Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    Ageno, Walter
    Gallus, Alexander S.
    Wittkowsky, Ann
    Crowther, Mark
    Hylek, Elaine M.
    Palareti, Gualtiero
    [J]. CHEST, 2012, 141 (02) : E44S - E88S
  • [2] [Anonymous], 2013, MED LETT DRUGS THER, V55, P53
  • [3] Heparin-induced thrombocytopenia
    Arepally, Gowthami M.
    Ortel, Thomas L.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (08) : 809 - 817
  • [4] High versus standard dose methylprednisolone in the acute phase of idiopathic thrombotic thrombocytopenic purpura: a randomized study
    Balduini, Carlo L.
    Gugliotta, Luigi
    Luppi, Mario
    Laurenti, Luca
    Klersy, Catherine
    Pieresca, Carla
    Quintini, Gerlando
    Iuliano, Francesco
    Re, Rossana
    Spedini, Pierangelo
    Vianelli, Nicola
    Zaccaria, Alfonso
    Pogliani, Enrico Maria
    Musso, Roberto
    Pallavicini, Enrico Bobbio
    Quarta, Giovanni
    Galieni, Piero
    Fragasso, Alberto
    Casella, Gianluca
    Noris, Patrizia
    Ascari, Edoardo
    [J]. ANNALS OF HEMATOLOGY, 2010, 89 (06) : 591 - 596
  • [5] Thrombotic thrombocytopenic purpura associated with clopidogrel.
    Bennett, CL
    Connors, JM
    Carwile, JM
    Moake, JL
    Bell, WR
    Tarantolo, SR
    McCarthy, LJ
    Sarode, R
    Hatfield, AJ
    Feldman, MD
    Davidson, CJ
    Tsai, HM
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (24) : 1773 - 1777
  • [6] Recombinant factor VIIa reverses the anticoagulant effect of the long-acting pentasaccharide idraparinux in healthy volunteers
    Bijsterveld, NR
    Vink, R
    van Aken, BE
    Fennema, H
    Peters, RJG
    Meijers, JCM
    Büller, HR
    Levi, M
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2004, 124 (05) : 653 - 658
  • [7] Ability of recombinant factor VIIa to reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers
    Bijsterveld, NR
    Moons, AH
    Boekholdt, SM
    van Aken, BE
    Fennema, H
    Peters, RJG
    Meijers, JCM
    Büller, HR
    Levi, M
    [J]. CIRCULATION, 2002, 106 (20) : 2550 - 2554
  • [8] Causes, prevention, and treatment of intravascular coagulation and disseminated intravascular coagulation
    Blaisdell, F. William
    [J]. JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2012, 72 (06) : 1719 - 1722
  • [9] Intravenous Lipid Emulsion Does Not Reverse Dabigatran-induced Anticoagulation in a Rat Model
    Blum, Jared
    Carreiro, Stephanie
    Hack, Jason B.
    [J]. ACADEMIC EMERGENCY MEDICINE, 2013, 20 (10) : 1022 - 1025
  • [10] The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital
    Borgman, Matthew A.
    Spinella, Philip C.
    Perkins, Jeremy G.
    Grathwohl, Kurt W.
    Repine, Thomas
    Beekley, Alec C.
    Sebesta, James
    Jenkins, Donald
    Wade, Charles E.
    Holcomb, John B.
    [J]. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 2007, 63 (04): : 805 - 813