BACKGROUND: Incidental durotomies occur in up to 17% of spinal operations. Controversy exists regarding the short- and long-term consequences of durotomies. PURPOSE: The primary aim of this study was to assess the effect of incidental durotomies on the immediate postoperative complications and patient-reported outcome measures. STUDY DESIGN: Prospective study. PATIENT SAMPLE: A total of 1,741 patients undergoing index lumbar spine fusion were selected from a multi-institutional prospective data registry. OUTCOME MEASURES: Patient-reported outcome measures used in this study included back pain (BP-Visual Analog Scale), leg pain (LP-Visual Analog Scale), and Oswestry Disability Index. METHODS: A total of 1,741 patients were selected from a multi-institutional prospective data registry, who underwent primary lumbar fusion for low back pain and/or radiculopathy between January 2003 and December 2010. We collected and analyzed data on patient demographics, postoperative complications, back pain, leg pain, and functional disability over 2 years, with risk-adjusted propensity score modeling. RESULTS: Incidental durotomies occurred in 70 patients (4%). Compared with the control group (n = 1,671), there was no significant difference in postoperative infection (p = .32), need for reoperation (p = .85), or symptomatic neurologic damage (p = .66). At 1- and 2-year follow-up, there was no difference in patient-reported outcomes of back pain (BP-Visual Analog Scale), leg pain (LP-Visual Analog Scale), or functional disability (Oswestry Disability Index) (p > .3), with results remaining consistent in the propensity-matched cohort analysis (p > .4). CONCLUSION: Within the context of an on-going debate on the consequences of incidental durotomy, we found no difference in neurologic symptoms, infection, reoperation, back pain, leg pain, or functional disability over a 2-year follow-up period. Published by Elsevier Inc.