Lipopolysaccharide rolls out the barrel

被引：16

作者：

Bishop, Russell E. ^{[1
,2
]}

机构：

[1] McMaster Univ, Dept Biochem & Biomed Sci, Hamilton, ON L8S 4K1, Canada

[2] McMaster Univ, Michael G DeGroote Inst Infect Dis Res, Hamilton, ON L8S 4K1, Canada

来源：

NATURE | 2014年 / 511卷 / 7507期

基金：

加拿大健康研究院;

关键词：

OUTER-MEMBRANE; STRUCTURAL BASIS; TRANSPORT;

D O I：

10.1038/nature13508

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Two crystal structures of the LptD–LptE protein complex reveal how the cell-wall component lipopolysaccharide is delivered and inserted into the external leaflet of the bacterial outer membrane. See Article p.52 & Letter p.108

引用

页码：37 / 38

页数：2

共 12 条

[1] PagP Crystallized from SDS/Cosolvent Reveals the Route for Phospholipid Access to the Hydrocarbon Ruler [J].

Cuesta-Seijo, Jose Antonio ;

Neale, Chris ;

Khan, M. Adil ;

Moktar, Joel ;

Tran, Christopher D. ;

Bishop, Russell E. ;

Pomes, Regis ;

Prive, Gilbert G. .

STRUCTURE, 2010, 18 (09) :1210-1219

[2] Structural basis for outer membrane lipopolysaccharide insertion [J].

Dong, Haohao ;

Xiang, Quanju ;

Gu, Yinghong ;

Wang, Zhongshan ;

Paterson, Neil G. ;

Stansfeld, Phillip J. ;

He, Chuan ;

Zhang, Yizheng ;

Wang, Wenjian ;

Dong, Changjiang .

NATURE, 2014, 511 (7507) :52-U569

[3] Regulated Assembly of the Transenvelope Protein Complex Required for Lipopolysaccharide Export [J].

Freinkman, Elizaveta ;

Okuda, Suguru ;

Ruiz, Natividad ;

Kahne, Daniel .

BIOCHEMISTRY, 2012, 51 (24) :4800-4806

[4] Transmembrane passage of hydrophobic compounds through a protein channel wall [J].

Hearn, Elizabeth M. ;

Patel, Dimki R. ;

Lepore, Bryan W. ;

Indic, Mridhu ;

van den Berg, Bert .

NATURE, 2009, 458 (7236) :367-U134

[5] Molecular Mechanism for Lateral Lipid Diffusion between the Outer Membrane External Leaflet and a β-Barrel Hydrocarbon Ruler [J].

Khan, M. Adil ;

Bishop, Russell E. .

BIOCHEMISTRY, 2009, 48 (41) :9745-9756

[6] Ligand-gated diffusion across the bacterial outer membrane [J].

Lepore, Bryan W. ;

Indic, Mridhu ;

Pham, Hannah ;

Hearn, Elizabeth M. ;

Patel, Dimki R. ;

van den Berg, Bert .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (25) :10121-10126

[7] Cytoplasmic ATP Hydrolysis Powers Transport of Lipopolysaccharide Across the Periplasm in E-coli [J].

Okuda, Suguru ;

Freinkman, Elizaveta ;

Kahne, Daniel .

SCIENCE, 2012, 338 (6111) :1214-1217

[8] Structural basis for lipopolysaccharide insertion in the bacterial outer membrane [J].

Qiao, Shuai ;

Luo, Qingshan ;

Zhao, Yan ;

Zhang, Xuejun Cai ;

Huang, Yihua .

NATURE, 2014, 511 (7507) :108-U523

[9] Lipid a modification systems in gram-negative bacteria [J].

Raetz, Christian R. H. ;

Reynolds, C. Michael ;

Trent, M. Stephen ;

Bishop, Russell E. .

ANNUAL REVIEW OF BIOCHEMISTRY, 2007, 76 :295-329

[10] Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa [J].

Srinivas, Nityakalyani ;

Jetter, Peter ;

Ueberbacher, Bernhard J. ;

Werneburg, Martina ;

Zerbe, Katja ;

Steinmann, Jessica ;

Van der Meijden, Benjamin ;

Bernardini, Francesca ;

Lederer, Alexander ;

Dias, Ricardo L. A. ;

Misson, Pauline E. ;

Henze, Heiko ;

Zumbrunn, Juerg ;

Gombert, Frank O. ;

Obrecht, Daniel ;

Hunziker, Peter ;

Schauer, Stefan ;

Ziegler, Urs ;

Kaech, Andres ;

Eberl, Leo ;

Riedel, Kathrin ;

DeMarco, Steven J. ;

Robinson, John A. .

SCIENCE, 2010, 327 (5968) :1010-1013

← 1 2 →