GP3: GenePix post-processing program for automated analysis of raw microarray data

被引：34

作者：

Fielden, MR ^{[1
]}

Halgren, RG ^{[1
]}

Dere, E ^{[1
]}

Zacharewski, TR ^{[1
]}

机构：

[1] Michigan State Univ, Inst Environm Toxicol, Natl Food Safety & Toxicol Ctr, Dept Biochem & Mol Biol, E Lansing, MI 48824 USA

来源：

BIOINFORMATICS | 2002年 / 18卷 / 05期

关键词：

D O I：

10.1093/bioinformatics/18.5.771

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Here we describe an automated and customizable program to correct, filter and normalize raw microarray data captured using GenePix, a commonly used microarray image analysis application. Files can be processed individually or in batch mode for increased throughput. User defined inputs specify the stringency of data filtering and the method and conditions of normalization. The output includes gene summaries for replicate spots and descriptive statistics for each experiment. The source code (Perl) can also be adapted to handle raw data output from other image analysis applications.

引用

页码：771 / 773

页数：3