Dendrimers: synthesis, applications, and properties

被引:713
|
作者
Abbasi, Elham [1 ]
Aval, Sedigheh Fekri [1 ,2 ]
Akbarzadeh, Abolfazl [1 ]
Milani, Morteza [1 ,3 ]
Nasrabadi, Hamid Tayefi [1 ]
Joo, Sang Woo [4 ]
Hanifehpour, Younes [4 ]
Nejati-Koshki, Kazem [1 ,2 ]
Pashaei-Asl, Roghiyeh [1 ]
机构
[1] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Nanotechnol, Tabriz 5154853431, Iran
[2] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Biotechnol, Tabriz 5154853431, Iran
[3] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Mol Med, Tabriz 5154853431, Iran
[4] Yeungnam Univ, Sch Mech Engn, Gyongsan 712749, South Korea
来源
基金
新加坡国家研究基金会;
关键词
Dendrimer; Pseudorotaxane; Nanoscale; PAMAM; MAGNETIC NANOPARTICLES; DENDRITIC POLYMERS; BIOMEDICAL APPLICATIONS; MOLECULAR RECOGNITION; PHOTODYNAMIC THERAPY; STARBURST DENDRIMERS; IN-VITRO; COMPLEXES; CHEMISTRY; MICELLES;
D O I
10.1186/1556-276X-9-247
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Dendrimers are nano-sized, radially symmetric molecules with well-defined, homogeneous, and monodisperse structure that has a typically symmetric core, an inner shell, and an outer shell. Their three traditional macromolecular architectural classes are broadly recognized to generate rather polydisperse products of different molecular weights. A variety of dendrimers exist, and each has biological properties such as polyvalency, self-assembling, electrostatic interactions, chemical stability, low cytotoxicity, and solubility. These varied characteristics make dendrimers a good choice in the medical field, and this review covers their diverse applications.
引用
收藏
页码:1 / 10
页数:10
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