Deprescribing guidelines: An international symposium on development, implementation, research and health professional education

被引:25
作者
Farrell, Barbara [1 ,2 ,3 ]
Conklin, James [1 ,4 ]
Dolovich, Lisa [5 ,6 ]
Irving, Hannah [1 ]
Maclure, Malcolm [7 ]
McCarthy, Lisa [5 ,8 ,9 ]
Moriarty, Frank [10 ]
Pottie, Kevin [1 ,2 ,11 ]
Raman-Wilms, Lalitha [5 ,12 ]
Reeve, Emily [13 ,14 ,15 ,16 ]
Thompson, Wade [17 ]
机构
[1] Bruyere Res Inst, 43 Bruyere St, Ottawa, ON K1N 5C8, Canada
[2] Univ Ottawa, Dept Family Med, Ottawa, ON, Canada
[3] Univ Waterloo, Sch Pharm, Waterloo, ON, Canada
[4] Concordia Univ, Montreal, PQ, Canada
[5] Univ Toronto, Leslie Dan Fac Pharm, 144 Coll St, Toronto, ON M5S 3M2, Canada
[6] McMaster Univ, Dept Family Med, Hamilton, ON, Canada
[7] Univ British Columbia, Dept Anesthesiol Pharmacol & Therapeut, 2775 Laurel St, Vancouver, BC V5Z 1M9, Canada
[8] Womens Coll Res Inst, 76 Grenville St, Toronto, ON M5S 1B2, Canada
[9] Univ Toronto, Dept Family & Community Med, Toronto, ON, Canada
[10] Royal Coll Surgeons Ireland, HRB Ctr Primary Hlth Care Res, 123 St Stephens Green, Dublin D02 YN77, Ireland
[11] Univ Ottawa, Dept Epidemiol & Community Med, Ottawa, ON, Canada
[12] Univ Manitoba, Rady Fac Hlth Sci, Coll Pharm, 750 McDermot Ave, Winnipeg, MB R3E 0T5, Canada
[13] Univ Sydney, NHMRC Cognit Decline Partnership Ctr, Royal North Shore Hosp,Northern Clin Sch, Kolling Inst Med Res,Fac Med & Hlth, St Leonards, NSW 2065, Australia
[14] Dalhousie Univ, Fac Med, Geriatr Med Res, Halifax, NS, Canada
[15] Dalhousie Univ, Coll Pharm, Halifax, NS, Canada
[16] Nova Scotia Hlth Author, Halifax, NS, Canada
[17] Univ Southern Denmark, Dept Publ Hlth, Res Unit Gen Practice, JB Winsowsvej 9, DK-5000 Odense C, Denmark
关键词
Deprescribing; Polypharmacy; Guidelines; Medication management; Implementation; Education; Research; ADVERSE DRUG-REACTIONS; REDUCE POLYPHARMACY; PEOPLES ATTITUDES; ECONOMIC BURDEN; OLDER-PEOPLE; IMPACT; EVENTS;
D O I
10.1016/j.sapharm.2018.08.010
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Deprescribing is a clinically important and feasible innovation that ensures medication efficacy, reduces harms, and mitigates polypharmacy. It involves reducing doses or stopping medications that are not useful, no longer needed, or which may be causing harm. It may also involve changing to a safer agent or using non-pharmacological approaches for care instead. Clinical guidelines combined with behaviour changes (of health care providers (HCPs), the public, and health care decision-makers) are needed to integrate deprescribing into routine practice. Using rigorous international standards, the Bruyere Research Institute Deprescribing Guidelines research team validated a ground-breaking deprescribing guideline methodology and developed or co-developed 5 evidence-based deprescribing guidelines. In March 2018, the team hosted an international symposium convening HCPs, researchers, public agencies, policymakers, and patient advocates in Ottawa, Ontario, Canada. This 3-day symposium aimed to facilitate knowledge exchange amongst guideline developers, users, and the public; initiate partnerships and collaborations for new deprescribing guideline recommendations and effectiveness research; and to continue work on HCP deprescribing education activities. An interprofessional planning committee developed an overall agenda, and small groups worked on session objectives and formats for different components: methods for rigorous deprescribing guideline development, implementation experiences, research/evaluation experiences and educational needs. Through a series of keynote speakers, panel discussions, and small working groups, the symposium provided a forum for participants to meet one another, learn about their different experiences with deprescribing guidelines, and develop collaborations for future initiatives. One hundred thirty participants, from 10 countries and representing over 100 institutions and organizations took part. Symposium proceedings are presented in this issue of RSAP for sharing with the wider community engaged in the care of patients with problematic polypharmacy.
引用
收藏
页码:780 / 789
页数:10
相关论文
共 32 条
  • [1] Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis
    Anderson, Kristen
    Stowasser, Danielle
    Freeman, Christopher
    Scott, Ian
    [J]. BMJ OPEN, 2014, 4 (12):
  • [2] [Anonymous], 2013, The Canadian Rx Atlas
  • [3] [Anonymous], 2017, MED HARM WHOS 3 GLOB, V2017, DOI [10.1016/S0140-6736(17)31047-4, DOI 10.1016/S0140-6736(17)31047-4]
  • [4] Bjerre LM, 2018, CAN FAM PHYSICIAN, V64, P17
  • [5] Emergency Hospitalizations for Adverse Drug Events in Older Americans
    Budnitz, Daniel S.
    Lovegrove, Maribeth C.
    Shehab, Nadine
    Richards, Chesley L.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (21) : 2002 - 2012
  • [6] Guideline for opioid therapy and chronic noncancer pain
    Busse, Jason W.
    Craigie, Samantha
    Juurlink, David N.
    Buckley, D. Norman
    Wang, Li
    Couban, Rachel J.
    Agoritsas, Thomas
    Akl, Elie A.
    Carrasco-Labra, Alonso
    Cooper, Lynn
    Cull, Chris
    da Costa, Bruno R.
    Frank, Joseph W.
    Grant, Gus
    Iorio, Alfonso
    Persaud, Navindra
    Stern, Sol
    Tugwell, Peter
    Vandvik, Per Olav
    Guyatt, Gordon H.
    [J]. CANADIAN MEDICAL ASSOCIATION JOURNAL, 2017, 189 (18) : E659 - E666
  • [7] Canadian Institute for Health Information, 2016, DRUG US SEN CAN 2016
  • [8] Validation of the theoretical domains framework for use in behaviour change and implementation research
    Cane, James
    O'Connor, Denise
    Michie, Susan
    [J]. IMPLEMENTATION SCIENCE, 2012, 7
  • [9] The Economic Burden of Inappropriate Drug Prescribing, Lack of Adherence and Compliance, Adverse Drug Events in Older People A Systematic Review
    Chiatti, Carlos
    Sustacchini, Silvia
    Furneri, Gianluca
    Mantovani, Lorenzo
    Cristiani, Marco
    Misuraca, Clementina
    Lattanzio, Fabrizia
    [J]. DRUG SAFETY, 2012, 35 : 73 - 87
  • [10] Reducing Prescriptions of Long-Acting Benzodiazepine Drugs in Denmark: A Descriptive Analysis of Nationwide Prescriptions during a 10-Year Period
    Eriksen, Sophie Isabel
    Bjerrum, Lars
    [J]. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2015, 116 (06) : 499 - 502