Palladium/Silver-Cocatalyzed Tandem Reactions of Oxabenzonorbornadienes with Substituted Arylacetylenes: A Simple Method for the Preparation of 1,2-Diarylethanones and 1,2-Diary Diarylacetylenes

被引：27
作者：
Chen, Jingchao [1 ]
Liu, Shanshan [1 ]
Zhou, Yongyun [1 ]
Li, Sifeng [1 ]
Lin, Chengyuan [2 ]
Bian, Zhaoxiang [2 ]
Fan, Baomin [1 ]
机构：
[1] Yunnan Minzu Univ, YMU HKBU Joint Lab Tradit Nat Med, Kunming 650500, Yunnan, Peoples R China
[2] Hong Kong Baptist Univ, Sch Chinese Med, Hong Kong, Hong Kong, Peoples R China
来源：
ORGANOMETALLICS | 2015年 / 34卷 / 17期
基金：
中国国家自然科学基金; 芬兰科学院;
关键词：
RING-OPENING REACTIONS; OXABICYCLIC ALKENES; 2+2 CYCLOADDITION; TERMINAL ALKYNES; BICYCLIC ALKENES; ORGANIC HALIDES; DERIVATIVES; NORBORNADIENES;
D O I：
10.1021/acs.organomet.5b00551
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The effective synthesis of 1,2-diarylethanones was achieved using palladium(II) acetate [Pd(OAc)(2)] and silver triflate (AgOTf) as cocatalysts from various oxabenzo-norbomadiene derivatives and substituted arylacetylenes via tandem reactions under mild conditions. Exploration of the oxabenzonorbomadiene substrates showed that the 1,2-diarylacetylenes were obtained from adjacent alkoxy substituted oxabenzonorbornadiene derivatives. Preliminary mechanistic studies indicate that the AgOTf served as an indispensable catalyst, and the mechanism of the tandem reaction was proposed.
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收藏
页码：4318 / 4322
页数：5
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