Shigella in Senegal (1993-1994): Distribution through serovar, sensibility to antibiotics and virulence

被引：3

作者：

Gassama, A ^{[1
]}

Boye, CS ^{[1
]}

Aidara, A ^{[1
]}

Raphenon, G ^{[1
]}

Samb, A ^{[1
]}

Mboup, S ^{[1
]}

机构：

[1] CHU A LE DANTEC, BACTERIOL LAB, DAKAR, SENEGAL

来源：

MEDECINE ET MALADIES INFECTIEUSES | 1997年 / 27卷 / 03期

关键词：

Shigella; serovar; susceptibility; virulence;

D O I：

10.1016/S0399-077X(97)80163-1

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

This study was made on 90 strains collected from various health units. Strains were identified by biotyping and serotyping with a predominance of Shigella flexneri (38.9%), S. dysenteriae (A(1)A(2)) (27,8%), S. sonnei (17.8%), S. boydii (C-1,C-3) (10%). Sensibility to antibiotics and determination of MIC (agar dilution) demonstrated high resistance to tetracycline (87.8%) with MIC > 256 mg/l, penicillin (17.8%) to sulfametoxazol, and trimethoprim (24.5%). All S. sonnei were resistant to this combination. Shigella strains were inhibited by cefozoline, cefotaxime, and imipenem. We also noticed a low resistance level to aminoglycosides like gentamicin (2.3%). In addition, virulence of the strains, determined by the Sereny test, showed that most of them induced kerato-conjuntivitis in guinea pigs, particularly S. boydii strains (100%). The percentage of invasive strains obtained in vitro in Hep(2) cells varied from 19% for S. sonnei to 32.4% for S. dysenteriae.

引用

页码：267 / 270

页数：4

共 8 条

[1]

ACAR J, 1985, PATHOL BIOL, V33, P295

[2]

CAVALLO JD, 1993, B SOC PATHOL EXOT, V86, P35

[3]

COURVALIN P, 1985, ANTIBIOGRAMME, P195

[4]

DEGLA C, 1992, THESIS DAKAR, P8