Antithrombotic Therapy in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention

被引：5

作者：

Camaj, Anton ^{[1
]}

Miller, Michael S. ^{[1
]}

Halperin, Jonathan L. ^{[1
]}

Giustino, Gennaro ^{[1
]}

机构：

[1] Icahn Sch Med Mt Sinai, Zena & Michael A Wiener Cardiovasc Inst, 1 Gustave L Levy Pl, New York, NY 10029 USA

来源：

CARDIOLOGY CLINICS | 2020年 / 38卷 / 04期

关键词：

Triple antithrombotic therapy; Dual antithrombotic therapy; Atrial fibrillation; Percutaneous coronary intervention; DUAL ANTIPLATELET THERAPY; ELUTING STENT IMPLANTATION; ORAL ANTICOAGULANT; ARTERY-DISEASE; TRIPLE THERAPY; FOCUSED UPDATE; OPEN-LABEL; ASPIRIN; CLOPIDOGREL; PCI;

D O I：

10.1016/j.ccl.2020.07.006

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patients with atrial fibrillation who undergo percutaneous coronary intervention with drug-eluting stent implantation often require oral anticoagulation (OAC) and antiplatelet therapies. Triple antithrombotic therapy (OAC, a P2Y12-receptor inhibitor, and aspirin) has been the default antithrombotic strategy. Evidence from randomized trials indicates, however, that a dual antithrombotic therapy strategy (OAC plus a P2Y12-receptor inhibitor) reduces bleeding risk without increasing the risk of ischemic events. This review provides an overview of advancements in this field as well as European and North American guidelines and consensus documents to inform clinical decision making around antithrombotic therapies for patients with atrial fibrillation who undergo percutaneous coronary intervention. © 2020 Elsevier Inc.

引用

页码：551 / 561

页数：11

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