2004 World Health Organization Classification of the Noninvasive Urothelial Neoplasms: Inherent Problems and Clinical Reflections

被引:19
作者
Montironi, Rodolfo [1 ]
Lopez-Beltran, Antonio [2 ]
Scarpelli, Marina [1 ]
Mazzucchelli, Roberta [1 ]
Cheng, Liany [3 ]
机构
[1] Polytech Univ Marche Reg Ancona, Sect Pathol Anat, Sch Med, I-60126 Ancona, Italy
[2] Univ Cordoba, Sch Med, Anat Pathol Unit, Cordoba, Spain
[3] Indiana Univ, Sch Med, Dept Pathol & Lab Med, Indianapolis, IN USA
关键词
Bladder neoplasms; Urothelial dysplasia; Carcinoma in situ; Urothelial papillary carcinoma; URINARY-BLADDER; BIOLOGIC IMPLICATIONS; FOLLOW-UP; PROGRESSION; TUMORS; CARCINOMA; WHO/ISUP; CANCER; GRADE; RECURRENCE;
D O I
10.1016/j.eursup.2008.12.004
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction, evidence acquisition and evidence synthesis: The 2004 World Health Organization (WHO) classification of tumors of the urinary system (ie, 2004 WHO classification) subdivides the noninvasive urothelial neoplasms into three major groups-flat, endophytic and papillary-depending on the relationship with the surface of the surrounding urothelial mucosa. Each lesion of these three groups is defined with strict morphologic criteria to provide more accurate information to urologists and oncologists in managing patients. Conclusions: There still is debate in the literature as to whether the 2004 WHO classification should be the only one used and whether the 1973 WHO system should be abandoned. Reporting both grades has been recommended. (c) 2008 European Association of Urology. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:453 / 457
页数:5
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