Microarrays for Mycobacterium tuberculosis

被引：30

作者：

Butcher, PD ^{[1
]}

机构：

[1] St George Hosp, Sch Med, London SW17 0RE, England

来源：

TUBERCULOSIS | 2004年 / 84卷 / 3-4期

基金：

英国惠康基金;

关键词：

Mycobacterium tuberculosis; microarrays; functional genomics; mRNA;

D O I：

10.1016/j.tube.2004.01.002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This special microarray issue of Tuberculosis recognises the important contributions of M. tuberculosis whole genome DNA microarrays to tuberculosis research by bringing together a range of papers that address M. tuberculosis physiology, host-pathogen interactions, mechanisms of drug action, in vitro and in vivo gene expression, host responses, comparative genomics and functional analysis of particular genes. A number of complete datasets of M. tuberculosis mRNA expression levels are provided to facilitate multiple cross-condition comparison. Microarrays represent one of the new functional genomics technologies exploiting genome sequence information that will bring us closer to realising the scientific and moral imperatives of better vaccines, diagnostics and new drugs for the control of tuberculosis throughout the world. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：131 / 137

页数：7

共 38 条

[1] Comparative genomics of BCG vaccines by whole-genome DNA microarray [J].

Behr, MA ;

Wilson, MA ;

Gill, WP ;

Salamon, H ;

Schoolnik, GK ;

Rane, S ;

Small, PM .

SCIENCE, 1999, 284 (5419) :1520-1523

[2] Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling [J].

Betts, JC ;

Lukey, PT ;

Robb, LC ;

McAdam, RA ;

Duncan, K .

MOLECULAR MICROBIOLOGY, 2002, 43 (03) :717-731

[3] Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis [J].

Betts, JC ;

McLaren, A ;

Lennon, MG ;

Kelly, FM ;

Lukey, PT ;

Blakemore, SJ ;

Duncan, K .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (09) :2903-2913

[4] Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv [J].

Camus, JC ;

Pryor, MJ ;

Médigue, C ;

Cole, ST .

MICROBIOLOGY-SGM, 2002, 148 :2967-2973

[5] Massive gene decay in the leprosy bacillus [J].

Cole, ST ;

Eiglmeier, K ;

Parkhill, J ;

James, KD ;

Thomson, NR ;

Wheeler, PR ;

Honoré, N ;

Garnier, T ;

Churcher, C ;

Harris, D ;

Mungall, K ;

Basham, D ;

Brown, D ;

Chillingworth, T ;

Connor, R ;

Davies, RM ;

Devlin, K ;

Duthoy, S ;

Feltwell, T ;

Fraser, A ;

Hamlin, N ;

Holroyd, S ;

Hornsby, T ;

Jagels, K ;

Lacroix, C ;

Maclean, J ;

Moule, S ;

Murphy, L ;

Oliver, K ;

Quail, MA ;

Rajandream, MA ;

Rutherford, KM ;

Rutter, S ;

Seeger, K ;

Simon, S ;

Simmonds, M ;

Skelton, J ;

Squares, R ;

Squares, S ;

Stevens, K ;

Taylor, K ;

Whitehead, S ;

Woodward, JR ;

Barrell, BG .

NATURE, 2001, 409 (6823) :1007-1011

[6] Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence [J].

Cole, ST ;

Brosch, R ;

Parkhill, J ;

Garnier, T ;

Churcher, C ;

Harris, D ;

Gordon, SV ;

Eiglmeier, K ;

Gas, S ;

Barry, CE ;

Tekaia, F ;

Badcock, K ;

Basham, D ;

Brown, D ;

Chillingworth, T ;

Connor, R ;

Davies, R ;

Devlin, K ;

Feltwell, T ;

Gentles, S ;

Hamlin, N ;

Holroyd, S ;

Hornby, T ;

Jagels, K ;

Krogh, A ;

McLean, J ;

Moule, S ;

Murphy, L ;

Oliver, K ;

Osborne, J ;

Quail, MA ;

Rajandream, MA ;

Rogers, J ;

Rutter, S ;

Seeger, K ;

Skelton, J ;

Squares, R ;

Squares, S ;

Sulston, JE ;

Taylor, K ;

Whitehead, S ;

Barrell, BG .

NATURE, 1998, 393 (6685) :537-+

[7] The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice [J].

Dahl, JL ;

Kraus, CN ;

Boshoff, HIM ;

Doan, B ;

Foley, K ;

Avarbock, D ;

Kaplan, G ;

Mizrahi, V ;

Rubin, H ;

Barry, CE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (17) :10026-10031

[8] In situ detection of Mycobacterium tuberculosis transcripts in human lung granulomas reveals differential gene expression in necrotic lesions [J].

Fenhalls, G ;

Stevens, L ;

Moses, L ;

Bezuidenhout, J ;

Betts, JC ;

van Helden, P ;

Lukey, PT ;

Duncan, K .

INFECTION AND IMMUNITY, 2002, 70 (11) :6330-6338

[9] Microarray analysis of the Mycobacterium tuberculosis transcriptional response to the acidic conditions found in phagosomes [J].

Fisher, MA ;

Plikaytis, BB ;

Shinnick, TM .

JOURNAL OF BACTERIOLOGY, 2002, 184 (14) :4025-4032

[10] Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains [J].

Fleischmann, RD ;

Alland, D ;

Eisen, JA ;

Carpenter, L ;

White, O ;

Peterson, J ;

DeBoy, R ;

Dodson, R ;

Gwinn, M ;

Haft, D ;

Hickey, E ;

Kolonay, JF ;

Nelson, WC ;

Umayam, LA ;

Ermolaeva, M ;

Salzberg, SL ;

Delcher, A ;

Utterback, T ;

Weidman, J ;

Khouri, H ;

Gill, J ;

Mikula, A ;

Bishai, W ;

Jacobs, WR ;

Venter, JC ;

Fraser, CM .

JOURNAL OF BACTERIOLOGY, 2002, 184 (19) :5479-5490

← 1 2 3 4 →