Detection of reactive oxygen and nitrogen species by EPR spin trapping

被引:176
|
作者
Villamena, FA
Zweier, JL
机构
[1] Ohio State Univ, Coll Med, Davis Heart & Lung Res Inst, Columbus, OH 43210 USA
[2] Ohio State Univ, Coll Med, Ctr Biomed EPR Spectroscopy & Imaging, Columbus, OH 43210 USA
关键词
D O I
10.1089/152308604773934387
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Electron paramagnetic resonance spin trapping has become an indispensable tool for the specific detection of reactive oxygen free radicals in biological systems. In this review we describe some of the advantages as well as some experimental considerations of this technique and how it can be applied to biological systems to measure oxidative stress.
引用
收藏
页码:619 / 629
页数:11
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