Synthesis of new ring-fused thiocarbamates by condensation of 2-thioxo- and 2-oxo-1,3-dialkyl-4,5-dihydroxy-4,5-diphenylimidazolidines with KSCN

被引：10

作者：

Baranov, Vladimir V. ^{[1
]}

Kravehenko, Angelina N. ^{[1
]}

Nelyubina, Yulia V. ^{[2
]}

机构：

[1] Russian Acad Sci, ND Zelinsky Inst Organ Chem, Moscow 119991, Russia

[2] Russian Acad Sci, AN Nesmeyanov Organoelement Cpds Inst, Moscow 119991, Russia

来源：

MENDELEEV COMMUNICATIONS | 2014年 / 24卷 / 02期

关键词：

D O I：

10.1016/j.mencom.2014.03.014

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reaction of 2-thioxo or 2-oxo-1,3-dialkyl-4,5-dihydroxy-4,5-diphenylimidazolidines with KSCN in acidified MeOH affords 4,6-dialkyl-3a,6a-diphenyltetrahydro-2H-imidazo[4,5-d]oxazole-2,5(3H)-dithiones or 4,6-dimethyl-3a,6a-diphenyl-2-thioxotetrahydro-2H-imidazo[4,5-d]oxazol-5(3H)-one, whose structure was proved by X-ray diffraction.

引用

页码：105 / 107

页数：3

共 16 条

[1] Biotin (Vitamin B8) Synthesis in Plants
Alban, Claude
[J]. BIOSYNTHESIS OF VITAMINS IN PLANTS: VITAMINS B6, B8, B9, C, E, K - PT B, 2011, 59 : 39 - 66
[2] Co-crystals in the series of 4,5-dihydroxy-4,5-diphenylimidazolidine-2-thiones
Baranov, Vladimir V.
Nelyubina, Yulia V.
Korlyukov, Aleksandr A.
Kravchenko, Angelina N.
[J]. MENDELEEV COMMUNICATIONS, 2009, 19 (04) : 211 - 213
[3] MECHANISTIC STUDIES IN THE CHEMISTRY OF THIOUREA .2. REACTION WITH BENZIL IN ACID-SOLUTION
BROAN, CJ
BUTLER, AR
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1991, (10): : 1501 - 1504
[4] Synthesis and biological evaluation of five-membered heterocycles fused to cyclopenta[c]thiophene as new antitumor agents
Dallemagne, P
Khanh, LP
Alsaïdi, A
Varlet, I
Collot, V
Paillet, M
Bureau, R
Rault, S
[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2003, 11 (07) : 1161 - 1167
[5] Biological Effects of Pharmacological Concentrations of Biotin
Fernandez-Mejia, Cristina
Lazo-de-la-Vega-Monroy, Maria-Luisa
[J]. JOURNAL OF EVIDENCE-BASED INTEGRATIVE MEDICINE, 2011, 16 (01): : 40 - 48
[6] Gimiene J., 2003, CARBOHYD RES, V338, P711
[7] Greenlee W. J., 1992, EP Patent, Patent No. 407102
[8] Kakanejadifard A, 2004, POL J CHEM, V78, P45
[9] Kamburg R, 2008, US Patent, Patent No. [227,838, 227838]
[10] Diastereoselective synthesis of 4,5-dihydroxyimidazolidin-2-ones (-thiones) and their structure
Kravchenko, A. N.
Baranov, V. V.
Nelyubina, Yu V.
Gazieva, G. A.
Svitan'ko, I. V.
[J]. RUSSIAN CHEMICAL BULLETIN, 2012, 61 (01) : 64 - 73

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