A new triterpene from the green walnut husks of Juglans mandshurica Maxim

被引：18
作者：
Zhou, Yuan-Yuan [1 ]
Song, Hong-Juan [1 ]
Guo, Shuang [1 ]
Wang, Ying [1 ]
Gao, Hui-Rui [1 ]
Zhang, Xiao-Juan [2 ]
Sun, Yan-Ping [1 ]
Liu, Yan [1 ]
Yang, Bing-You [1 ]
Kuang, Hai-Xue [1 ]
机构：
[1] Heilongjiang Univ Chinese Med, Coll Pharm, Harbin 150040, Heilongjiang, Peoples R China
[2] Heilongjiang Univ Chinese Med, Acad Res Dept, Harbin 150040, Heilongjiang, Peoples R China
来源：
JOURNAL OF NATURAL MEDICINES | 2019年 / 73卷 / 04期
基金：
美国国家科学基金会; 中国博士后科学基金; 黑龙江省自然科学基金;
关键词：
Juglans mandshurica Maxim; Triterpenes; Cytotoxicity; Antitumor; CYTOTOXICITY; TERPENOIDS; EXTRACTS; MARKERS; LEAF; ROOT;
D O I：
10.1007/s11418-019-01309-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A new triterpene named klodorol B (1), together with six known compounds, were isolated from the green walnut husks of Juglans mandshurica Maxim. Their structures were determined using spectroscopic methods on the basis of 1D and 2D NMR, and high-resolution electrospray ionization mass spectrometry. The isolated compounds were evaluated for their cytotoxic activities on human gastric carcinoma (BGC-823), human liver cancer (HepG-2) and human lung cancer (A549) cell lines.
引用
收藏
页码：800 / 804
页数：5
相关论文
共 50 条
[21]   JA, a new type of polyunsaturated fatty acid isolated from Juglans mandshurica Maxim, limits the survival and induces apoptosis of heptocarcinoma cells [J].
Xiu-Li Gao ;
Hua Lin ;
Wei Zhao ;
Ya-Qin Hou ;
Yong-Li Bao ;
Zhen-Bo Song ;
Lu-Guo Sun ;
Shang-Yi Tian ;
Biao Liu ;
Yu-Xin Li .
Apoptosis, 2016, 21 :340-350
[22]   JA, a new type of polyunsaturated fatty acid isolated from Juglans mandshurica Maxim, limits the survival and induces apoptosis of heptocarcinoma cells [J].
Gao, Xiu-Li ;
Lin, Hua ;
Zhao, Wei ;
Hou, Ya-Qin ;
Bao, Yong-Li ;
Song, Zhen-Bo ;
Sun, Lu-Guo ;
Tian, Shang-Yi ;
Liu, Biao ;
Li, Yu-Xin .
APOPTOSIS, 2016, 21 (03) :340-350
[23]   Phenolics and neolignans isolated from the fruits of Juglans mandshurica Maxim. and their effects on lipolysis in adipocytes [J].
Park, SeonJu ;
Kim, Nanyoung ;
Yoo, Guijae ;
Kim, Sang-Nam ;
Kwon, Hyun-Jung ;
Jung, Kiwon ;
Oh, Dong-Chan ;
Lee, Yun-Hee ;
Kim, Seung Hyun .
PHYTOCHEMISTRY, 2017, 137 :87-93
[24]   Cytotoxic lignans from the barks of Juglans mandshurica [J].
Zhang, Xiao-Ning ;
Bai, Ming ;
Cheng, Zhuo-Yang ;
Yu, Zhi-Guo ;
Huang, Xiao-Xiao .
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 20 (05) :494-499
[25]   A cytotoxic compound from the leaves of Juglans mandshurica [J].
Li, Zhi Bo ;
Bao, Yong Ming ;
Chen, Hong Bo ;
Wang, Jing Yun ;
Hu, Jie Han ;
An, Li Jia .
CHINESE CHEMICAL LETTERS, 2007, 18 (07) :846-848
[26]   A cytotoxic compound from the leaves of Juglans mandshurica [J].
Zhi Bo Li a Yong Ming Bao a Hong Bo Chen b Jing Yun Wang a Jie Han Hu c Li Jia An a a Department of Bioscience and Biotechnology Dalian University of Technology Dalian China b School of Chemical Engineering Dalian University of Technology Dalian China c Dalian Institute of Chemical Physics The Chinese Academy of Sciences Dalian China .
ChineseChemicalLetters, 2007, (07) :846-848
[27]   Diversity in Fruit Morphology and Nutritional Composition of Juglans mandshurica Maxim in Northeast China [J].
Li, Zhixin ;
Wang, Weihuai ;
Zhang, Haixiao ;
Liu, Jinhong ;
Shi, Baoying ;
Dai, Weizhao ;
Liu, Kewu ;
Zhang, Hanguo .
FRONTIERS IN PLANT SCIENCE, 2022, 13
[28]   Juglans mandshurica Maxim extracts exhibit antitumor activity on HeLa cells in vitro [J].
Xin, Nian ;
Hasan, Murtaza ;
Li, Wei ;
Li, Yan .
MOLECULAR MEDICINE REPORTS, 2014, 9 (04) :1313-1318
[29]   Chemical constituents from the leaves of Juglans mandshurica [J].
Da Lei Yao ;
Chang Hao Zhang ;
Jie Luo ;
Mei Jin ;
Ming Shan Zheng ;
Jiong Mo Cui ;
Jong Keun Son ;
Gao Li .
Archives of Pharmacal Research, 2015, 38 :480-484
[30]   Molecular Cloning, Expression Analysis and Subcellular Localization of LEAFY in Juglans mandshurica Maxim [J].
Liu, Chunping ;
Lu, Xiujun ;
Song, Jiaxing ;
Zhou, Qiang ;
Sun, Xiaomei ;
Deng, Jifeng ;
Zhang, Lijie .
POLISH JOURNAL OF ENVIRONMENTAL STUDIES, 2022, 31 (02) :1713-1725
12345