Outcome of patients with IDH1/2-mutated post myeloproliferative neoplasm AML in the era of IDH inhibitors

被引：45

作者：

Chifotides, Helen T. ^{[1
]}

Masarova, Lucia ^{[1
]}

Alfayez, Mansour ^{[1
]}

Daver, Naval ^{[1
]}

Alvarado, Yesid ^{[1
]}

Jabbour, Elias ^{[1
]}

Konopleva, Marina ^{[1
]}

Kantarjian, Hagop M. ^{[1
]}

Patel, Keyur P. ^{[2
]}

DiNardo, Courtney D. ^{[1
]}

Verstovsek, Srdan ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, 1515 Holcombe Blvd,Unit 428, Houston, TX 77030 USA

[2] Univ Texas MD Anderson Canc Ctr, Dept Hematopathol, Houston, TX 77030 USA

来源：

BLOOD ADVANCES | 2020年 / 4卷 / 21期

基金：

美国国家卫生研究院;

关键词：

LEUKEMIC TRANSFORMATION; CELL TRANSPLANTATION; MUTATIONS; MYELOFIBROSIS; RUXOLITINIB; PROGNOSIS;

D O I：

10.1182/bloodadvances.2020001528

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：5336 / 5342

页数：7

共 41 条

[21] Isocitrate dehydrogenase mutations in myeloid malignancies [J].

Medeiros, B. C. ;

Fathi, A. T. ;

DiNardo, C. D. ;

Pollyea, D. A. ;

Chan, S. M. ;

Swords, R. .

LEUKEMIA, 2017, 31 (02) :272-281

[22] The role of IDH mutations in acute myeloid leukemia [J].

Montalban-Bravo, Guillermo ;

DiNardo, Courtney D. .

FUTURE ONCOLOGY, 2018, 14 (10) :979-993

[23] Validation of the WHO-defined 20% circulating blasts threshold for diagnosis of leukemic transformation in primary myelofibrosis [J].

Mudireddy, Mythri ;

Gangat, Naseema ;

Hanson, Curtis A. ;

Ketterling, Rhett P. ;

Pardanani, Animesh ;

Tefferi, Ayalew .

BLOOD CANCER JOURNAL, 2018, 8

[24] How I treat the blast phase of Philadelphia chromosome-negative myeloproliferative neoplasms [J].

Odenike, Olatoyosi .

BLOOD, 2018, 132 (22) :2339-2350

[25] Clinical outcomes of IDH2-mutated advanced-phase Ph-negative myeloproliferative neoplasms treated with enasidenib [J].

Patel, Anand A. ;

Cahill, Kirk ;

Charnot-Katsikas, Angella ;

Liu, Hongtao ;

Gurbuxani, Sandeep ;

Thirman, Michael ;

Kosuri, Satyajit ;

Artz, Andrew S. ;

Larson, Richard A. ;

Stock, Wendy ;

Segal, Jeremy ;

Odenike, Olatoyosi .

BRITISH JOURNAL OF HAEMATOLOGY, 2020, 190 (01) :E48-E51

[26] Venetoclax for AML: changing the treatment paradigm [J].

Pollyea, Daniel A. ;

Amaya, Maria ;

Strati, Paolo ;

Konopleva, Marina Y. .

BLOOD ADVANCES, 2019, 3 (24) :4326-4335

[27] Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia [J].

Pollyea, Daniel A. ;

Tallman, Martin S. ;

de Botton, Stephane ;

Kantarjian, Hagop M. ;

Collins, Robert ;

Stein, Anthony S. ;

Frattini, Mark G. ;

Xu, Qiang ;

Tosolini, Alessandra ;

See, Wendy L. ;

MacBeth, Kyle J. ;

Agresta, Samuel, V ;

Attar, Eyal C. ;

DiNardo, Courtney D. ;

Stein, Eytan M. .

LEUKEMIA, 2019, 33 (11) :2575-2584

[28] Safety and efficacy of combined ruxolitinib and decitabine in accelerated and blast-phase myeloproliferative neoplasms [J].

Rampai, Raajit K. ;

Mascarenhas, John O. ;

Kosiorek, Heidi E. ;

Price, Leah ;

Berenzon, Dmitriy ;

Hexner, Elizabeth ;

Abboud, Camille N. ;

Kremyanskaya, Marina ;

Weinberg, Rona Singer ;

Salama, Mohamed E. ;

Menghrajani, Kamal ;

Najfeld, Vesna ;

Sandy, Lonette ;

Heaney, Mark L. ;

Levine, Ross L. ;

Mesa, Ruben A. ;

Dueck, Amylou C. ;

Goldberg, Judith D. ;

Hoffman, Ronald .

BLOOD ADVANCES, 2018, 2 (24) :3572-3580

[29] Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia [J].

Roboz, Gail J. ;

DiNardo, Courtney D. ;

Stein, Eytan M. ;

de Botton, Stephane ;

Mims, Alice S. ;

Prince, Gabrielle T. ;

Altman, Jessica K. ;

Arellano, Martha L. ;

Donnellan, Will ;

Erba, Harry P. ;

Mannis, Gabriel N. ;

Pollyea, Daniel A. ;

Stein, Anthony S. ;

Uy, Geoffrey L. ;

Watts, Justin M. ;

Fathi, Amir T. ;

Kantarjian, Hagop M. ;

Tallman, Martin S. ;

Choe, Sung ;

Dai, David ;

Fan, Bin ;

Wang, Hongfang ;

Zhang, Vickie ;

Yen, Katharine E. ;

Kapsalis, Stephanie M. ;

Hickman, Denice ;

Liu, Hua ;

Agresta, Samuel, V ;

Wu, Bin ;

Attar, Eyal C. ;

Stone, Richard M. .

BLOOD, 2020, 135 (07) :463-471

[30] Prognostic impact of RAS-pathway mutations in patients with myelofibrosis [J].

Santos, Fabio P. S. ;

Getta, Bartlomiej ;

Masarova, Lucia ;

Famulare, Christopher ;

Schulman, Jessica ;

Datoguia, Tarcila S. ;

Puga, Renato D. ;

Alves Paiva, Raquel de Melo ;

Arcila, Maria E. ;

Hamerschlak, Nelson ;

Kantarjian, Hagop M. ;

Levine, Ross L. ;

Campregher, Paulo Vidal ;

Rampal, Raajit K. ;

Verstovsek, Srdan .

LEUKEMIA, 2020, 34 (03) :799-810

← 1 2 3 4 5 →