SURGICAL MANAGEMENT OF THE ADRENAL GLAND TUMORS - SINGLE CENTER EXPERIENCE

被引:6
作者
Musina, A. M. [1 ,2 ]
Hutanu, I [1 ,2 ]
Scripcariu, D., V [1 ,2 ]
Anitei, M. G. [1 ,2 ]
Filip, B. [1 ,2 ]
Hogea, M. [2 ]
Radu, I [1 ,2 ]
Gavrilescu, M. M. [1 ,2 ]
Panuta, A. [1 ,2 ]
Buna-Arvinte, M. [1 ,2 ]
Moraru, V. G. [1 ,2 ]
Scripcariu, V [1 ,2 ]
机构
[1] Grigore T Popa Univ Med & Pharm, Surg Dept, Iasi, Romania
[2] Reg Inst Oncol Iasi, Surg Oncol Unit 1, Iasi, Romania
关键词
adrenal gland; adrenalectomy; primary tumor; metastatic tumor; LAPAROSCOPIC ADRENALECTOMY; CUSHINGS-SYNDROME; OUTCOMES; ERA; PHEOCHROMOCYTOMA;
D O I
10.4183/aeb.2020.208
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Context. Incidentally discovered solid adrenal tumors must be evaluated from two points of view: the risk of malignancy and the secretory feature. Objective. Our aim was to evaluate the surgical technique option in relation with clinical and histopathologic features. Design. We performed a retrospective study that included patients with adrenal gland tumors. Subjects and methods. All patients were operated between 2012 and 2019 by the same surgical team in a single center. Results. The batch included 102 patients with adrenal tumors operated through open surgery (OS, n=41) and laparoscopic surgery (LS, n=61). Tumor localization was especially on the right adrenal gland (n=52, 50.98%). Primary origin of the adrenal gland tumors was in 82 cases (80.39%) and a metastatic origin in 16 cases. Average dimension for surgical resected tumors was 4.02 cm (0.9-12 cm) for the LS group as compared to 7.22 cm (1.3-19 cm) for OS group with a predominant type of surgery represented by adrenalectomy and a conversion rate of 2.94%. The hospital stay was 7.22 days (5-12 days) in the LS group versus 12.72 days (6-57 days) in OS group with significant differences (p<0.01). Also, the postoperative recovery was significantly different (6.5 days versus 2.62 days. p<0.01). Conclusion. Laparoscopic approach represents the gold standard in adrenal gland tumors less than five centimeters in size. Adrenalectomy is mostly performed by LS and adenoma is the most frequent histopathologic type, while pheochromocytoma is operated through OS. LS has a significantly reduced hospitalization and postoperative stay compared to OS.
引用
收藏
页码:208 / 215
页数:8
相关论文
共 27 条
[1]   A G-quadruplex-binding compound shows potent activity in human gemcitabine-resistant pancreatic cancer cells [J].
Ahmed, Ahmed Abdullah ;
Marchetti, Chiara ;
Ohnmacht, Stephan A. ;
Neidle, Stephen .
SCIENTIFIC REPORTS, 2020, 10 (01)
[2]   Retroperitoneal adrenalectomy-learning curve, practical tips and tricks, what limits its wider uptake [J].
Alesina, Pier Francesco .
GLAND SURGERY, 2019, 8 :S36-S40
[3]  
Ali Zafar, 2019, J Coll Physicians Surg Pak, V29, pS16, DOI 10.29271/jcpsp.2019.06.S16
[4]   Adrenalectomy for familial pheochromocytoma in the laparoscopic era [J].
Brunt, LM ;
Lairmore, TC ;
Doherty, GM ;
Quasebarth, MA ;
DeBenedetti, M ;
Moley, JF .
ANNALS OF SURGERY, 2002, 235 (05) :713-720
[5]   CT Characteristics of Pheochromocytoma: Relevance for the Evaluation of Adrenal Incidentaloma [J].
Canu, Letizia ;
Van Hemert, Janna A. W. ;
Kerstens, Michiel N. ;
Hartman, Robert P. ;
Khanna, Aakanksha ;
Kraljevic, Ivana ;
Kastelan, Darko ;
Badiu, Corin ;
Ambroziak, Urszula ;
Tabarin, Antoine ;
Haissaguerre, Magalie ;
Buitenwerf, Edward ;
Visser, Anneke ;
Mannelli, Massimo ;
Arlt, Wiebke ;
Chortis, Vasileios ;
Bourdeau, Isabelle ;
Gagnon, Nadia ;
Buchy, Marie ;
Borson-Chazot, Francoise ;
Deutschbein, Timo ;
Fassnacht, Martin ;
Hubalewska-Dydejczyk, Alicja ;
Motyka, Marcin ;
Rzepka, Ewelina ;
Casey, Ruth T. ;
Challis, Benjamin G. ;
Quinkler, Marcus ;
Vroonen, Laurent ;
Spyroglou, Ariadni ;
Beuschlein, Felix ;
Lamas, Cristina ;
Young, William F. ;
Bancos, Irina ;
Timmers, Henri J. L. M. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2019, 104 (02) :312-318
[6]   TREATMENT OF CUSHING'S SYNDROME : WHAT PLACE FOR MEDICAL TREATMENT? [J].
Chabre, O. ;
Cristante, J. .
ACTA ENDOCRINOLOGICA-BUCHAREST, 2019, 15 (02) :237-243
[7]   A systematic review on COVID-19: urological manifestations, viral RNA detection and special considerations in urological conditions [J].
Chan, Vinson Wai-Shun ;
Chiu, Peter Ka-Fung ;
Yee, Chi-Hang ;
Yuan, Yuhong ;
Ng, Chi-Fai ;
Teoh, Jeremy Yuen-Chun .
WORLD JOURNAL OF UROLOGY, 2021, 39 (09) :3127-3138
[8]   Laparoscopic adrenalectomy - Ascending the learning curve [J].
David, G ;
Yoav, M ;
Gross, D ;
Reissman, P .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2004, 18 (05) :771-773
[9]   Laparoscopic adrenalectomy: preoperative data, surgical technique and clinical outcomes [J].
Di Buono, Giuseppe ;
Buscemi, Salvatore ;
Lo Monte, Attilio Ignazio ;
Geraci, Girolamo ;
Sorce, Vincenzo ;
Citarrella, Roberto ;
Gulotta, Eliana ;
Palumbo, Vincenzo Davide ;
Fazzotta, Salvatore ;
Gulotta, Leonardo ;
Albano, Domenico ;
Galia, Massimo ;
Romano, Giorgio ;
Agrusa, Antonino .
BMC SURGERY, 2019, 18 (Suppl 1)
[10]   Challenges of training in adrenal surgery [J].
Gimm, Oliver ;
Duh, Quan-Yang .
GLAND SURGERY, 2019, 8 :S3-S9