Synthesis of organosulfides using transition-metal-catalyzed substitution reactions: to construct exergonic reactions employing metal inorganic and organic co-substrate/co-product methods

被引：40

作者：

Arisawa, Mieko ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Dept Organ Chem, Aoba Ku, Sendai, Miyagi 9808578, Japan

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 23期

关键词：

Synthesis of organosulfides; Organic co-substrate/co-product; Metal inorganic co-substrate/co-product; Exergonic reactions; Catalytic substitution reaction; ARYL HALIDES; BOND FORMATION; EQUILIBRIUM ACIDITIES; DIARYL DISULFIDES; EXCHANGE-REACTION; DIRECT THIOLATION; HIGHLY EFFICIENT; BENZYL KETONES; SULFENIC ACIDS; H BONDS;

D O I：

10.1016/j.tetlet.2014.04.081

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalyst changes the course of a reaction without affecting the relative thermodynamic stability of substrates and products, and a catalytic reaction must be exergonic in order to obtain high yields of the product and to attain reasonable reaction rates. In the case that the desired reaction is in equilibrium or is endergonic, devices for making products thermodynamically more stable than substrates are needed. In this review, the transition-metal-catalyzed synthesis of organosulfides using a substitution reaction is summarized, where metal inorganic and organic co-substrate/co-product methods are used in developing exergonic reactions. (C) 2014 Published by Elsevier Ltd.

引用

页码：3391 / 3399

页数：9

共 80 条

[1] Efficient syntheses of AZD4407 via thioether formation by nucleophilic attack of organometallic species on sulphur [J].