Hepatitis B, C, Treponema pallidum and Toxoplasma gondii co-infections in HIV infected patients

Background: Some infections share Common modes of transmission with HIV and have the potential to change the course of the latter. Aim: To assess the prevalence of hepatitis 8 virus (HBV) hepatitis C virus (HCV), Treponema pallidum and Toxoplasma gondii co-infections in HIV-1 infected patients followed at a university hospital. Material and methods: Clinical records of HIV-positive individuals were reviewed. Me analysis included: demographical data, hepatitis B surface antigen HBsAg), IgM and IgG anti-HBc, antibodies, anti-HCV antibodies, RPR or VDRL test and IqG anti T gondii antibodies. Results. Three hundred ninety five patients (aged 16 to 89 years. 359 males) were included in the review. Seventy, nine percent bad been tested for HBV status with HBsAg and the global HIV-HBV co-infection prevalence was 6.1%. A subgroup of 190 individuals were tested for HBV infection with HBsAg and IgM/IgG anti-HBc markers. of these, 46% fufilled co-infection criteria: eight with acute bepatitis B, 11 with chronic hepatitis B and 69 with inactive HBV infection. The frequency of HIV-HBV co-infection axis 48016 and 22% among men and women respectively (NS). HCV-HIV co-infection was detected in 3%, syphilis-HIV co-infection in 21% and T gondii-HIV co-infection in 26%. Conclusions: In this cohort, HIV infection is accompanied by a high prevalence of other co-infections, particularly HBV among men (Rev Med Chile 2009; 137 641-8).