Relationship between supernormal sectors of retinal nerve fibre layer and axial length in normal eyes

被引:31
|
作者
Yamashita, Takehiro [1 ]
Kii, Yuya [1 ]
Tanaka, Minoru [1 ]
Yoshinaga, Wakako [1 ]
Yamashita, Toshifumi [1 ]
Nakao, Kumiko [1 ]
Sakamoto, Taiji [1 ]
机构
[1] Kagoshima Univ, Grad Sch Med & Dent Sci, Dept Ophthalmol, Kagoshima 890, Japan
关键词
glaucoma; myopia; pseudo-negative; pseudo-positive; retina; RNFL colour code; OPTICAL COHERENCE TOMOGRAPHY; OPEN-ANGLE GLAUCOMA; MYOPIA; THICKNESS; PERFORMANCE; VARIABILITY; PREVALENCE; JAPANESE; DEFECTS; TAJIMI;
D O I
10.1111/aos.12382
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To determine the effect of the axial length on the supernormal and false-positive sectors of the peripapillary retinal nerve fibre layer (RNFL) in healthy eyes using the normative database embedded in a spectral domain optical coherence tomographic (SD-OCT) instrument. Methods: This was a prospective, observational cross -sectional study. The right eyes of 126 healthy young volunteers were studied. The RNFL thickness was measured by SD-OCT in twelve 30-degree sectors (clock hours) around the optic disc. The sectors whose RNFL thickness was <5% probability level were labelled as false-positive sectors. The sectors >95% probability level were labelled as supernormal sectors. The relationships between the axial length and rates of supernormal and false-positive sectors were investigated. Results: A longer axial length was significantly associated with an increase in the rates of supernormal thickness in sector 8 (odds ratio, [OR], 1.494; p = 0.010) and sector 10 (OR, 1.529; p = 0.008). The supernormal sectors were mainly located in the temporal region. A longer axial length was significantly associated with a higher rates of false positives in sector 5 (OR, 1.789; p = 0.017), sector 6 (OR, 2.305; p < 0.001) and sector 12 (OR, 2.277; p = 0.035). Conclusions: The axial length was significantly related to the rates of supernormal and false-positive sectors even in healthy eyes. These findings indicate that the specificity and sensitivity of SD-OCT will be affected especially in eyes with longer axial lengths.
引用
收藏
页码:E481 / E487
页数:7
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