TLR7: A new sensor of viral infection

被引：139

作者：

Crozat, K ^{[1
]}

Beutler, B ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Immunol, La Jolla, CA 92037 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2004年 / 101卷 / 18期

关键词：

D O I：

10.1073/pnas.0401347101

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：6835 / 6836

页数：2

共 27 条

[1] Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3 [J].

Alexopoulou, L ;

Holt, AC ;

Medzhitov, R ;

Flavell, RA .

NATURE, 2001, 413 (6857) :732-738

[2] Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition [J].

Bauer, S ;

Kirschning, CJ ;

Häcker, H ;

Redecke, V ;

Hausmann, S ;

Akira, S ;

Wagner, H ;

Lipford, GB .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (16) :9237-9242

[3] Innate immune sensing and its roots: the story of endotoxin [J].

Beutler, B ;

Rietschel, ET .

NATURE REVIEWS IMMUNOLOGY, 2003, 3 (02) :169-176

[4] Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo [J].

Boczkowski, D ;

Nair, SK ;

Snyder, D ;

Gilboa, E .

JOURNAL OF EXPERIMENTAL MEDICINE, 1996, 184 (02) :465-472

[5] Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA [J].

Diebold, SS ;

Kaisho, T ;

Hemmi, H ;

Akira, S ;

Sousa, CRE .

SCIENCE, 2004, 303 (5663) :1529-1531

[6]

Du X, 2000, EUR CYTOKINE NETW, V11, P362

[7] The toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily [J].

Heil, F ;

Ahmad-Nejad, P ;

Hemmi, H ;

Hochrein, H ;

Ampenberger, F ;

Gellert, T ;

Dietrich, H ;

Lipford, G ;

Takeda, K ;

Akira, S ;

Wagner, H ;

Bauer, S .

EUROPEAN JOURNAL OF IMMUNOLOGY, 2003, 33 (11) :2987-2997

[8] Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8 [J].

Heil, F ;

Hemmi, H ;

Hochrein, H ;

Ampenberger, F ;

Kirschning, C ;

Akira, S ;

Lipford, G ;

Wagner, H ;

Bauer, S .

SCIENCE, 2004, 303 (5663) :1526-1529

[9] Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA [J].

Heiser, A ;

Maurice, MA ;

Yancey, DR ;

Wu, NZ ;

Dahm, P ;

Pruitt, SK ;

Boczkowski, D ;

Nair, SK ;

Ballo, MS ;

Gilboa, E ;

Vieweg, J .

JOURNAL OF IMMUNOLOGY, 2001, 166 (05) :2953-2960

[10] Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway [J].

Hemmi, H ;

Kaisho, T ;

Takeuchi, O ;

Sato, S ;

Sanjo, H ;

Hoshino, K ;

Horiuchi, T ;

Tomizawa, H ;

Takeda, K ;

Akira, S .

NATURE IMMUNOLOGY, 2002, 3 (02) :196-200

← 1 2 3 →