Pandemic and Avian Influenza A Viruses in Humans Epidemiology, Virology, Clinical Characteristics, and Treatment Strategy

被引：50

作者：

Li, Hui ^{[1
,3
]}

Cao, Bin ^{[1
,2
]}

机构：

[1] Capital Med Univ, Dept Resp Med, 10 You An Men Wai Xi Tou Tiao, Beijing 10069, Peoples R China

[2] China Japan Friendship Hosp, Lab Clin Microbiol & Infect Dis, Ctr Resp & Crit Care Med, 2 Ying Hua Dong Jie, Beijing 100029, Peoples R China

[3] 2 Ying Hua Dong Jie, Beijing 100029, Peoples R China

来源：

CLINICS IN CHEST MEDICINE | 2017年 / 38卷 / 01期

关键词：

Pandemic influenza virus; Avian influenza A viruses; Epidemiology; Virology; Clinical characteristics; Treatment; TO-PERSON TRANSMISSION; PRIMARY VIRAL PNEUMONIA; CRITICALLY-ILL PATIENTS; H7N9; VIRUS; NEURAMINIDASE INHIBITORS; BACTERIAL COINFECTION; RISK-FACTORS; CORTICOSTEROID-THERAPY; MECHANICAL VENTILATION; ANTIVIRAL RESISTANCE;

D O I：

10.1016/j.ccm.2016.11.005

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The intermittent outbreak of pandemic influenza and emergence of novel avian influenza A virus is worldwide threat. Although most patients present with mild symptoms, some deteriorate to severe pneumonia and even death. Great progress in the understanding of the mechanism of disease pathogenesis and a series of vaccines has been promoted worldwide; however, incidence, morbidity, and mortality remains high. To step up vigilance and improve pandemic preparedness, this article elucidates the virology, epidemiology, pathogenesis, clinical characteristics, and treatment of human infections by influenza A viruses, with an emphasis on the influenza A(H1N1)pdm09, H5N1, and H7N9 subtypes.

引用

页码：59 / +

页数：13

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