Photo-tunable multicolour fluorescence imaging based on self-assembled fluorogenic nanoparticles

被引：48

作者：

Montalti, Marco ^{[1
]}

Battistelli, Giulia ^{[1
]}

Cantelli, Andrea ^{[1
]}

Genovese, Damiano ^{[1
]}

机构：

[1] Univ Bologna, Dept Chem G Ciamician, I-40126 Bologna, Italy

来源：

CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 40期

基金：

欧洲研究理事会;

关键词：

PROBES; SPECTROSCOPY; PROTEINS; EMISSION; THERAPY; DESIGN; WATER; DYES; RED;

D O I：

10.1039/c3cc48464e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Non-fluorescent nanoparticles resulting from the self-assembly of a new perylene diimide behave as fluorogenic probes for biological cells under physiological conditions giving a dosage-dependent green or red fluorescence and showing very low cytotoxicity. The emission colour can be tuned by photo-irradiation to achieve multicolour labelling.

引用

收藏

页码：5326 / 5329

页数：4

相关论文

共 35 条

[1] Sensors and regulators of intracellular pH [J].

Casey, Joseph R. ;

Grinstein, Sergio ;

Orlowski, John .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2010, 11 (01) :50-61

[2]

Chan J, 2012, NAT CHEM, V4, P973, DOI [10.1038/NCHEM.1500, 10.1038/nchem.1500]

[3] Solvent and substituent effects on aggregation constants of perylene bisimide π-stacks - a linear free energy relationship analysis [J].

Chen, Zhijian ;

Fimmel, Benjamin ;

Wuerthner, Frank .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2012, 10 (30) :5845-5855

[4] Upconversion nanoparticles and their composite nanostructures for biomedical imaging and cancer therapy [J].

Cheng, Liang ;

Wang, Chao ;

Liu, Zhuang .

NANOSCALE, 2013, 5 (01) :23-37

[5] Structural and molecular interrogation of intact biological systems [J].

Chung, Kwanghun ;

Wallace, Jenelle ;

Kim, Sung-Yon ;

Kalyanasundaram, Sandhiya ;

Andalman, Aaron S. ;

Davidson, Thomas J. ;

Mirzabekov, Julie J. ;

Zalocusky, Kelly A. ;

Mattis, Joanna ;

Denisin, Aleksandra K. ;

Pak, Sally ;

Bernstein, Hannah ;

Ramakrishnan, Charu ;

Grosenick, Logan ;

Gradinaru, Viviana ;

Deisseroth, Karl .

NATURE, 2013, 497 (7449) :332-+

[6] PHOTOCHEMISTRY OF 3,4,9,10-PERYLENETETRACARBOXYLIC DIANHYDRIDE DYES .3. SINGLET AND TRIPLET EXCITED-STATE PROPERTIES OF THE BIS(2,5-DI-TERT-BUTYLPHENYL)IMIDE DERIVATIVE [J].

FORD, WE ;

KAMAT, PV .

JOURNAL OF PHYSICAL CHEMISTRY, 1987, 91 (25) :6373-6380

[7] Prevention of Self-Quenching in Fluorescent Silica Nanoparticles by Efficient Energy Transfer [J].

Genovese, Damiano ;

Bonacchi, Sara ;

Juris, Riccardo ;

Montalti, Marco ;

Prodi, Luca ;

Rampazzo, Enrico ;

Zaccheroni, Nelsi .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (23) :5965-5968

[8] Single molecule spectroscopy of organic dye nanoparticles [J].

Gesquiere, AJ ;

Uwada, T ;

Asahi, T ;

Masuhara, H ;

Barbara, PF .

NANO LETTERS, 2005, 5 (07) :1321-1325

[9] Molecular Assemblies of Perylene Bisimide Dyes in Water [J].

Goerl, Daniel ;

Zhang, Xin ;

Wuerthner, Frank .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 51 (26) :6328-6348

[10] Integrating genetic approaches into the discovery of anticancer drugs [J].

Hartwell, LH ;

Szankasi, P ;

Roberts, CJ ;

Murray, AW ;

Friend, SH .

SCIENCE, 1997, 278 (5340) :1064-1068

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